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View Structure Prediction Details

Protein: stck-PB
Organism: Drosophila melanogaster
Length: 345 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for stck-PB.

Description E-value Query
Range
Subject
Range
gi|73947291 - gi|73947291|ref|XP_541354.2| PREDICTED: similar to Zinc finger protein 606 (Zinc finger protein 328)...
496.0 [0..3] [344..2507]

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Predicted Domain #1
Region A:
Residues: [1-195]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPVQVQAAN MSLGAMHCTR CADGFEPTEK IVNSNGELWH TQCFVCAQCF RPFQDGIFYE  60
   61 FEGRKYCERD FHVLFAPCCN KCGEFVIGRV IKAMSASWHP QCFRCQLCAK ELADCGFIKN 120
  121 QNRALCHECN AKVKAEITGR YVCQKCHGLI DEEPLRFRGE VYHGYHFSCT ACGTELDSTA 180
  181 REVKSRPGLA ANDMN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 48.69897
Match: 2i13A
Description: No description for 2i13A was found.

Predicted Domain #2
Region A:
Residues: [196-345]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELYCLRCHDK MGIPICGACR RPIEERVVTA LGKHWHVEHF VCAKCEKPFL GHRHYEKRGL  60
   61 AYCETHYHQL FGNLCFVCNQ VIGGDVFTAL NKAWCVHHFA CSVCDTKMTQ KSKFYEYDEK 120
  121 PVCKKCYDRF PNELRRRLRT AHEMTMKKNT 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.30103
Match: 2gliA
Description: Five-finger GLI1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.70988788192472 bayes_pls_golite062009
nucleic acid binding 4.58713908116892 bayes_pls_golite062009
DNA binding 4.56219307357342 bayes_pls_golite062009
transcription activator activity 3.52873291636993 bayes_pls_golite062009
transcription factor activity 3.50954949535763 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.22082323675675 bayes_pls_golite062009
binding 3.10743787485868 bayes_pls_golite062009
sequence-specific DNA binding 2.53101891154822 bayes_pls_golite062009
cytoskeletal protein binding 2.22104591928521 bayes_pls_golite062009
chromatin binding 2.18464662431232 bayes_pls_golite062009
protein binding 2.05530362750351 bayes_pls_golite062009
transcription repressor activity 1.64349785387632 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.63161912031789 bayes_pls_golite062009
transcription factor binding 1.39608963544799 bayes_pls_golite062009
molecular transducer activity 1.12277938241964 bayes_pls_golite062009
signal transducer activity 1.12277938241964 bayes_pls_golite062009
structure-specific DNA binding 0.93314267845352 bayes_pls_golite062009
transcription cofactor activity 0.77874411480713 bayes_pls_golite062009
tubulin binding 0.744315484113484 bayes_pls_golite062009
microtubule binding 0.576452165256057 bayes_pls_golite062009
double-stranded DNA binding 0.53991278722671 bayes_pls_golite062009
receptor activity 0.36635758793995 bayes_pls_golite062009
catalytic activity 0.245893663605433 bayes_pls_golite062009
transcription corepressor activity 0.10558148421807 bayes_pls_golite062009

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