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View Structure Prediction Details

Protein: CG18749-PB, FBpp...
Organism: Drosophila melanogaster
Length: 491 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG18749-PB, FBpp....

Description E-value Query
Range
Subject
Range
gi|73952895 - gi|73952895|ref|XP_862207.1| PREDICTED: similar to prolyl 4-hydroxylase, alpha I subunit isoform 1 p...
526.0 [0..7] [485..1]

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Predicted Domain #1
Region A:
Residues: [1-170]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYILKKLTFI GFLSACFINC QGFVNSNPKK SYAASTMELM KLLEVEDELV DNLKGYVKTL  60
   61 KMKFNLMERS LIDMSRENME MKSDYESYLG NPLNSFRLIH RLHTSWRKWY QYAIKVENNA 120
  121 LGHIENARLM RKMLPTSSDL QQACRGIHDL MYFYDLKPEE LAAGNLAGYS 

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 63.004365
Match: PF08336.2
Description: No description for PF08336.2 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [171-284]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPGTGLTAYD CLALGEFGVQ NQKDDLAEAW YNLSLTRFDN IIEKYQVHKA WALLLAKNKQ  60
   61 LTEAFQHFEN KPEGIVASNE VIHFEGVLAT TQNCTAVVQK PSKKLHCRYN TSTT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.69897
Match: 1tjcA
Description: Crystal structure of peptide-substrate-binding domain of human type I collagen prolyl 4-hydroxylase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
procollagen-proline 4-dioxygenase activity 7.0422525853653 bayes_pls_golite062009
procollagen-proline dioxygenase activity 7.0422525853653 bayes_pls_golite062009
peptidyl-proline dioxygenase activity 7.0422525853653 bayes_pls_golite062009
peptidyl-proline 4-dioxygenase activity 7.0422525853653 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors 5.01373106146099 bayes_pls_golite062009
binding 2.14253214573541 bayes_pls_golite062009
protein binding 1.65083457326273 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [285-491]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PFTRIAPLKM EELGLDPYMV VFHDVIYDTE IDGMLNSSDF GLSESVSGLK SEVRTSKDSH  60
   61 IVDAKTLNER VTDMTGLSME MSDPFSLINY GLGGHFILHH DFHEYTNTTR LKQGDRIATV 120
  121 LFYLREVDSG GATVFPMLNI TVMPKKGSAV FWYNLHNSGA VNSKTLHTAC PVISGSKYVL 180
  181 TKWINELPQM FVTPCMKDSN LRPPQKE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 5.05
Match: 2hbtA
Description: No description for 2hbtA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle