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View Structure Prediction Details

Protein: Syt4-PA
Organism: Drosophila melanogaster
Length: 474 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Syt4-PA.

Description E-value Query
Range
Subject
Range
gi|17946418 - gi|17946418|gb|AAL49242.1| RE67111p [Drosophila melanogaster]
408.0 [0..1] [474..1]

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Predicted Domain #1
Region A:
Residues: [1-83]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEEYIPDAS VMDTIVPAIL GLTAAAVLSS VACICARQMR LRNKKQSQHD ASFPFQPTRR  60
   61 PTAVRSPSGQ PPHYLKKSPS PTG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.07
Match: 1zzaA
Description: Solution NMR Structure of the Membrane Protein Stannin
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [84-178]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKQMGLLSPM QDQSTSPIAQ PNVKYSEEGD GPAQHAEQQN GNQLTVVDGN GLKHSLHNSL  60
   61 HHSPVETIAN GSVTITLDDH SLTNGKELTV TDQYG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.39794
Match: 1tbnA
Description: NMR STRUCTURE OF A PROTEIN KINASE C-G PHORBOL-BINDING DOMAIN, MINIMIZED AVERAGE STRUCTURE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.16347270289353 bayes_pls_golite062009
protein binding 1.19117920066014 bayes_pls_golite062009
signal transducer activity 1.07277438393187 bayes_pls_golite062009
molecular transducer activity 1.07277438393187 bayes_pls_golite062009
GTPase regulator activity 0.598251633160064 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 0.578046214771465 bayes_pls_golite062009
transcription regulator activity 0.225436367274486 bayes_pls_golite062009
enzyme regulator activity 0.224266644517051 bayes_pls_golite062009
guanyl-nucleotide exchange factor activity 0.0251407403506928 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [179-474]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KLGTIYFKLR YLAERNALMV SIIRCRGLPC KGGSSGTGDI PTGMNGRTQA ATDPYVKLQL  60
   61 LPDKQHKVKT RVVRNTRNPV YDEDFTFYGL NMNDLQNMSL HFVILSFDRY SRDDVIGEVV 120
  121 CPLTSIEIGD ISKEALSISK EIQPRSLKIR AQGRGELLIS LCWQPAAGRL TVVLLKARNL 180
  181 PRMDVTGLAD PYVKIYLLYN GQRIAKKKTH VKKRTLSPVF NESFAFDIPA AEGAGASLEG 240
  241 VSLELMLLDW DRVTKNEVIG RLELGGPNSS STALNHWNEV CNSPRRQIAE WHKLNE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 70.09691
Match: 1dqvA
Description: Synaptogamin I
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle