YRC Public Data Repository - Protein Structure Prediction

Protein:	asf1-PB, asf1-PA
Organism:	Drosophila melanogaster
Length:	218 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for asf1-PB, asf1-PA.

Description	E-value	Query Range	Subject Range
gi\|54641715, gi\|... - gi\|54641715\|gb\|EAL30465.1\| GA21747 [Drosophila pseudoobscura pseudoobscura], gi\|125977862\|ref\|XP_001... gi\|54641715\|gb\|E... - GA21747-PA [Drosophila pseudoobscura], GA21747 [Drosophila pseudoobscura pseudoobscura]	322.0	[0..1]	[218..1]
AS1AB_XENLA - Histone chaperone asf1a-B OS=Xenopus laevis GN=asf1ab PE=2 SV=1	312.0	[0..1]	[199..1]
ASF1B_XENTR - Histone chaperone asf1b OS=Xenopus tropicalis GN=asf1b PE=2 SV=1	310.0	[0..1]	[199..1]
AS1BA_DANRE - Histone chaperone asf1b-A OS=Danio rerio GN=asf1ba PE=2 SV=1	309.0	[0..1]	[198..1]
gi\|213512016, gi... - gi\|27705326\|ref\|XP_215389.1\| PREDICTED: similar to ASF1 anti-silencing function 1 homolog A [Rattus ...	308.0	[0..1]	[202..1]
gi\|126310500 - gi\|126310500\|ref\|XP_001369330.1\| PREDICTED: hypothetical protein [Monodelphis domestica] gi\|109072878 - gi\|109072878\|ref\|XP_001110511.1\| PREDICTED: similar to ASF1 anti-silencing function 1 homolog A [Mac... gi\|224048235 - gi\|224048235\|ref\|XP_002190080.1\| PREDICTED: ASF1 anti-silencing function 1 homolog A [Taeniopygia gu... gi\|217273036 - gi\|217273036\|gb\|ACK28129.1\| ASF1 anti-silencing function 1 homolog A (predicted) [Oryctolagus cunicu... ASF1A - ASF1 anti-silencing function 1 homolog A (S. cerevisiae) ASF1_CHICK - Histone chaperone ASF1 OS=Gallus gallus GN=ASF1 PE=1 SV=1 gi\|57031837 - gi\|57031837\|ref\|XP_533479.1\| PREDICTED: similar to ASF1 anti-silencing function 1 homolog A [Canis f...	306.0	[0..1]	[202..1]
ASF1A_MOUSE - Histone chaperone ASF1A OS=Mus musculus GN=Asf1a PE=1 SV=1	306.0	[0..1]	[202..1]
gi\|62901888 - gi\|62901888\|gb\|AAY18895.1\| CGI-98 [synthetic construct]	303.0	[0..2]	[202..26]

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Predicted Domain #1

Region A:
Residues: [1-218]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKVHITNVV VLDNPSSFFN PFQFELTFEC IEELKEDLEW KMIYVGSAES EEHDQVLDTI  60
   61 YVGPVPEGRH IFVFQADPPD VSKIPEPDAV GVTIVLLTCS YRGQEFVRVG YYVNNDYADP 120
  121 EMRENPPTKP LFEKLTRNIL ASKPRVTRFK INWDYGHING NGNGVENGHQ DEMATDGPST 180
  181 SEAASAVIHP EDDNSLAMPM ENGIKALNEN SNSLAMEC

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	76.30103
Match:	2io5A
Description:	No description for 2io5A was found.

Predicted functions:

Term	Confidence	Notes
histone binding	4.79132023578789	bayes_pls_golite062009
binding	2.53764463034371	bayes_pls_golite062009
transcription regulator activity	2.5158947712633	bayes_pls_golite062009
protein binding	2.37105076370775	bayes_pls_golite062009
chromatin binding	0.27260556482582	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: