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View Structure Prediction Details

Protein: PGRP-SB1-PA
Organism: Drosophila melanogaster
Length: 190 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PGRP-SB1-PA.

Description E-value Query
Range
Subject
Range
gi|37665227, gi|... - gi|37665227|emb|CAD89130.1| peptidoglycan recognition protein SB1 [Drosophila melanogaster], gi|3766...
221.0 [0..1] [190..1]
gi|37665245 - gi|37665245|emb|CAD89139.1| peptidoglycan recognition protein SB1 [Drosophila simulans]
212.0 [0..1] [187..1]
gi|60688419, gi|... - gi|71896011|ref|NP_001025626.1| pglyrp1 protein [Xenopus (Silurana) tropicalis], gi|60688419|gb|AAH9...
202.0 [0..6] [188..1]
PGRP2_HOLDI - Peptidoglycan-recognition protein 2 OS=Holotrichia diomphalia GN=PGRP-2 PE=1 SV=1
195.0 [0..6] [190..1]
PGRP4_MOUSE - Peptidoglycan recognition protein 4 OS=Mus musculus GN=Pglyrp4 PE=2 SV=1
195.0 [0..23] [188..210]
gi|4104409 - gi|4104409|gb|AAD02029.1| cuticular molt protein precursor [Calpodes ethlius]
194.0 [0..4] [190..1]

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Predicted Domain #1
Region A:
Residues: [1-190]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTSTAISFV AALVLCCLAL SANALQIEPR SSWGAVSARS PSRISGAVDY VIIHHSDNPN  60
   61 GCSTSEQCKR MIKNIQSDHK GRRNFSDIGY NFIVAGDGKV YEGRGFGLQG SHSPNYNRKS 120
  121 IGIVFIGNFE RSAPSAQMLQ NAKDLIELAK QRGYLKDNYT LFGHRQTKAT SCPGDALYNE 180
  181 IKTWPHWRQN 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 49.522879
Match: 1s2jA
Description: Crystal structure of the Drosophila pattern-recognition receptor PGRP-SA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidoglycan binding 9.32313496679335 bayes_pls_golite062009
peptidoglycan receptor activity 6.51660037886232 bayes_pls_golite062009
pattern recognition receptor activity 6.45255811818702 bayes_pls_golite062009
N-acetylmuramoyl-L-alanine amidase activity 5.29207604418857 bayes_pls_golite062009
pattern binding 4.06455798515101 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 3.20235326428146 bayes_pls_golite062009
receptor activity 2.69681086194598 bayes_pls_golite062009
signal transducer activity 2.24692953747972 bayes_pls_golite062009
molecular transducer activity 2.24692953747972 bayes_pls_golite062009
binding 1.78736719382897 bayes_pls_golite062009
muramyl dipeptide binding 1.16811676642278 bayes_pls_golite062009
hydrolase activity 1.14017500144843 bayes_pls_golite062009
0.808368163500401 bayes_pls_golite062009
catalytic activity 0.628556091191359 bayes_pls_golite062009
0.60706691535931 bayes_pls_golite062009
protein binding 0.175384917086218 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle