YRC Public Data Repository - Protein Structure Prediction

Protein:	Pros26-PA
Organism:	Drosophila melanogaster
Length:	235 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Pros26-PA.

Description	E-value	Query Range	Subject Range
PSA_PYRAB - Proteasome subunit alpha OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=psmA PE=3 SV=1 PSMA_PYRAB - Proteasome subunit alpha OS=Pyrococcus abyssi GN=psmA PE=3 SV=1	218.0	[0..2]	[233..6]
PSA_PYRHO - Proteasome subunit alpha OS=Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC ... PSMA_PYRHO - Proteasome subunit alpha OS=Pyrococcus horikoshii GN=psmA PE=3 SV=1	215.0	[0..2]	[231..6]
PSA_PYRFU - Proteasome subunit alpha OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) GN=p... PSMA_PYRFU - Proteasome subunit alpha OS=Pyrococcus furiosus GN=psmA PE=3 SV=1	215.0	[0..2]	[233..6]
PSA_THEK1 - Proteasome subunit alpha OS=Thermococcus sp. (strain JCM 11816 / KS-1) GN=psmA PE=3 SV=1 PSA_THEK1, PSMA_... - Proteasome subunit alpha OS=Thermococcus sp. (strain KS-1) GN=psmA PE=3 SV=1, Proteasome subunit alp... gi\|11265988 - pir\|\|T43887 proteasome alpha chain [imported] - Thermococcus sp	212.0	[0..2]	[231..6]
gi\|65304454 - gi\|65304454\|emb\|CAI76833.1\| proteasome subunit, putative [Theileria annulata] gi\|84997473 - gi\|84997473\|ref\|XP_953458.1\| proteasome subunit [Theileria annulata strain Ankara]	212.0	[0..1]	[222..1]
PSMA_PYRKO - Proteasome subunit alpha OS=Pyrococcus kodakaraensis GN=psmA PE=3 SV=1 PSA_THEKO - Proteasome subunit alpha OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) GN=ps...	212.0	[0..2]	[231..6]
gi\|68351418 - gi\|68351418\|gb\|EAN32181.1\| proteasome subunit alpha type, putative [Theileria parva] gi\|71029642 - gi\|71029642\|ref\|XP_764464.1\| proteasome subunit alpha type [Theileria parva strain Muguga]	211.0	[0..1]	[222..1]
PSA4_SPIOL - Proteasome subunit alpha type-4 OS=Spinacia oleracea GN=PAC1 PE=2 SV=1	210.0	[0..1]	[220..1]
PSMA_METKA - Proteasome subunit alpha OS=Methanopyrus kandleri GN=psmA PE=3 SV=1 PSA_METKA - Proteasome subunit alpha OS=Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938) ...	210.0	[0..2]	[227..6]
PSMA_METJA - Proteasome subunit alpha OS=Methanocaldococcus jannaschii GN=psmA PE=1 SV=1 PSA_METJA - Proteasome subunit alpha OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JC...	209.0	[0..4]	[233..7]

Back

Predicted Domain #1

Region A:
Residues: [1-235]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRLGFEQFP DYQVPGMKHP DFSPYESNGG SIVAIAGDDF AVIAADTRLS SGYNIHSRTQ  60
   61 SKLFKLSPQT VLGSAGCWAD TLSLTGSIKV RMQSYEHTHL RTMTTEAVAQ MLSIAMYNRR 120
  121 FFPYYVSNIL AGIDNEGKGV VYSYDPIGHC EKATYRAGGT AGTLLQPVLD NQIGHKNMNL 180
  181 EDADKIKLTK ERAVSVASDT FISAAERDIY TGDSVLINII TKDGIEVRTL TLRQD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.221849
Match:	1iruM
Description:	Proteasome beta subunit (catalytic)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
endopeptidase activity	6.91642761177919	bayes_pls_golite062009
peptidase activity	6.84511694091156	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	6.5973571808298	bayes_pls_golite062009
hydrolase activity	4.47652590304822	bayes_pls_golite062009
threonine-type endopeptidase activity	2.98214579292788	bayes_pls_golite062009
threonine-type peptidase activity	2.98214579292788	bayes_pls_golite062009
catalytic activity	1.19663085909195	bayes_pls_golite062009
binding	1.18139971903068	bayes_pls_golite062009
nucleic acid binding	0.448212653390607	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: