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View Structure Prediction Details

Protein: Prosbeta2-PA
Organism: Drosophila melanogaster
Length: 272 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Prosbeta2-PA.

Description E-value Query
Range		 Subject
Range
PSB7_MOUSE - Proteasome subunit beta type-7 OS=Mus musculus GN=Psmb7 PE=1 SV=1
gi|55715937 - gb|AAH86112.1| Unknown (protein for MGC:98506) [Xenopus laevis]
 277.0 [0..1] [270..1]
gi|62898273, gi|... - gi|62898273|dbj|BAD97076.1| proteasome beta 7 subunit proprotein variant [Homo sapiens], gi|62897575...
gi|114626634 - gi|114626634|ref|XP_520247.2| PREDICTED: proteasome beta 7 subunit isoform 5 [Pan troglodytes]
 274.0 [0..1] [270..1]
gi|109110260 - gi|109110260|ref|XP_001083368.1| PREDICTED: proteasome beta 7 subunit [Macaca mulatta]
 274.0 [0..1] [270..1]
PSB7_RAT - Proteasome subunit beta type-7 OS=Rattus norvegicus GN=Psmb7 PE=1 SV=1
 273.0 [0..1] [270..1]
PSMB7 - proteasome (prosome, macropain) subunit, beta type, 7
gi|208967176 - gi|208967176|dbj|BAG73602.1| proteasome (prosome, macropain) subunit, beta type, 7 [synthetic constr...
 271.0 [0..1] [270..1]
gi|2582504 - gi|2582504|gb|AAB82570.1| 20S proteasome beta2 subunit [Drosophila melanogaster]
 270.0 [0..1] [272..1]

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Predicted Domain #1
Region A:
Residues: [1-272] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLDNARDLP RAGFNFDNCK RNATLLNRGF KPPTTTKTGT TIVGIIYKDG VILGADTRAT  60
   61 EGPIVSDKNC AKIHYLAKNI YCCGAGTAAD TEMTTDLISS QLELHRLQTD REVRVVAANT 120
  121 MLKQMLFRYQ GHISAALVLG GVDKTGPHIY SIHPHGSSDK LPYATMGSGS LAAMTVFESR 180
  181 WKPDLSEEEG KKLVRDAIAS GVFNDLGSGS NIDLCVIRKG SVEYLRNYEL ANKKGKRQLD 240
  241 YRFKTGTSTV LHTNIKDLLV TERVQAVPME IS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 63.221849
Match: 1iruI
Description: Proteasome beta subunit (catalytic)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
endopeptidase activity 6.91642761177919 bayes_pls_golite062009
peptidase activity 6.84511694091156 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 6.5973571808298 bayes_pls_golite062009
hydrolase activity 4.47652590304822 bayes_pls_golite062009
threonine-type endopeptidase activity 2.98214579292788 bayes_pls_golite062009
threonine-type peptidase activity 2.98214579292788 bayes_pls_golite062009
catalytic activity 1.19663085909195 bayes_pls_golite062009
binding 0.982918122186083 bayes_pls_golite062009
nucleic acid binding 0.448212653390607 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle