YRC Public Data Repository - Protein Structure Prediction

Protein:	CG6662-PA
Organism:	Drosophila melanogaster
Length:	254 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG6662-PA.

Description	E-value	Query Range	Subject Range
gi\|50540310, gi\|... - gi\|50540310\|ref\|NP_001002621.1\| hypothetical protein LOC436894 [Danio rerio], gi\|49904398\|gb\|AAH7596...	185.0	[0..3]	[245..4]
gi\|11385535 - gi\|11385535\|gb\|AAG34850.1\|AF244707_1 glutathione S-transferase GST 42 [Zea mays]	177.0	[0..16]	[236..1]
CG6776-PA - This gene is referred to in FlyBase by the symbol Dmel\CG6776 (CG6776, FBgn0035904). It is a protein...	177.0	[0..1]	[244..1]
gi\|15808378 - gi\|15808378\|gb\|AAL08414.1\| omega class glutathione-S-transferase [Takifugu rubripes]	175.0	[0..8]	[245..10]
gi\|46518247 - gi\|46518247\|emb\|CAD89618.1\| omega class glutathione S-transferase [Crassostrea gigas]	172.0	[0..1]	[246..1]
gi\|47222286 - gi\|47222286\|emb\|CAG05035.1\| unnamed protein product [Tetraodon nigroviridis]	172.0	[0..1]	[245..1]
gi\|125979571, gi... - gi\|54640802\|gb\|EAL29553.1\| GA19859 [Drosophila pseudoobscura pseudoobscura], gi\|125979571\|ref\|XP_001... gi\|125979571\|ref... - GA19859-PA [Drosophila pseudoobscura], GA19859 [Drosophila pseudoobscura pseudoobscura]	172.0	[0..1]	[248..1]
gi\|17385642 - gi\|17385642\|dbj\|BAB32446.2\| glutathione S-transferase [Matricaria chamomilla]	170.0	[0..18]	[235..2]
gi\|50749765 - gi\|50749765\|ref\|XP_421747.1\| PREDICTED: similar to glutathione-S-transferase homolog isoform 2 [Gall...	170.0	[0..4]	[239..6]

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Predicted Domain #1

Region A:
Residues: [1-254]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNTQHLTIG SPKPVFPDDG ILKLYSMRFC PYAHRVHLVL DAKKIPYHAI YINLRDKPEW  60
   61 FSLVSSSTKV PALELVKEQG NPVLIESLII CDYLDEKYPE VPLYPKDLLK KAQEKILIER 120
  121 FGQFINAFYY LLLHDNPEQL VDTDHYAGLV VYEEELKRRC TKFFGGDSPG MLDYMMWPWC 180
  181 ERFDSLKYTF EQKFELSPER FPTLIKWRDL MIQDRAVKCF YLDGQTHAKY MNSRRSGQAD 240
  241 YNMLYNEAKR VKLG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	42.39794
Match:	1eemA
Description:	Class omega GST
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
antioxidant activity	3.26520127994042	bayes_pls_golite062009
peroxidase activity	2.96616905270619	bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor	2.96616905270619	bayes_pls_golite062009
peroxiredoxin activity	2.12777217096121	bayes_pls_golite062009
thioredoxin peroxidase activity	1.96134566495756	bayes_pls_golite062009
glutathione peroxidase activity	1.84498211544043	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	1.66635539173786	bayes_pls_golite062009
disulfide oxidoreductase activity	1.14955061683324	bayes_pls_golite062009
catalytic activity	0.672192331361968	bayes_pls_golite062009
binding	0.419658151482326	bayes_pls_golite062009
oxidoreductase activity	0.314980210547407	bayes_pls_golite062009
protein binding	0.034515546627104	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: