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View Structure Prediction Details

Protein: CG6776-PA
Organism: Drosophila melanogaster
Length: 241 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG6776-PA.

Description E-value Query
Range
Subject
Range
gi|50540310, gi|... - gi|50540310|ref|NP_001002621.1| hypothetical protein LOC436894 [Danio rerio], gi|49904398|gb|AAH7596...
188.0 [0..1] [238..1]
gi|54640801, gi|... - gi|54640801|gb|EAL29552.1| GA19847-PA [Drosophila pseudoobscura], gi|125979569|ref|XP_001353817.1| G...
180.0 [0..10] [241..474]
gi|11385535 - gi|11385535|gb|AAG34850.1|AF244707_1 glutathione S-transferase GST 42 [Zea mays]
176.0 [0..16] [233..1]
gi|220958330, gi... - gi|220960194|gb|ACL92633.1| se-PA [synthetic construct], gi|220958330|gb|ACL91708.1| se-PA [syntheti...
se-PA - The gene sepia is referred to in FlyBase by the symbol Dmel\se (CG6781, FBgn0086348). It is a protei...
172.0 [0..1] [240..1]
gi|47222286 - gi|47222286|emb|CAG05035.1| unnamed protein product [Tetraodon nigroviridis]
172.0 [0..1] [238..1]
gi|17385642 - gi|17385642|dbj|BAB32446.2| glutathione S-transferase [Matricaria chamomilla]
169.0 [0..18] [227..2]
gi|125575475, gi... - gi|37536330|ref|NP_922467.1| putative glutathione S-transferase [Oryza sativa (japonica cultivar-gro...
gi|125532731 - gi|125532731|gb|EAY79296.1| hypothetical protein OsI_34422 [Oryza sativa Indica Group]
168.0 [0..17] [233..4]
gi|46518247 - gi|46518247|emb|CAD89618.1| omega class glutathione S-transferase [Crassostrea gigas]
168.0 [0..1] [239..1]

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Predicted Domain #1
Region A:
Residues: [1-241]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSGKHLAKG SPKPVLPDDG VLRLYSMRFC PYAQRAHLVL NAKNVPYHSV YINLTEKPEW  60
   61 LVEVSPLLKV PALQLVAEKG EPSLIESLII AEYLDDKYPE NPLLPKDPLK RAQDKILLER 120
  121 FSSITSAFIN ILVQGTGLED YWTALDIFEE ELTKRGTPYF GGNKPGFVDY MIWPWFERLS 180
  181 VIELKLQKEY NFNESRFPKI TKWIALLKAD SVVQSFYATP EQHNEFWRTR KAGNANYDLL 240
  241 A

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 40.69897
Match: 1eemA
Description: Class omega GST
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
antioxidant activity 3.26520127994042 bayes_pls_golite062009
peroxidase activity 2.96616905270619 bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor 2.96616905270619 bayes_pls_golite062009
peroxiredoxin activity 2.12777217096121 bayes_pls_golite062009
thioredoxin peroxidase activity 1.96134566495756 bayes_pls_golite062009
glutathione peroxidase activity 1.84498211544043 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 1.66635539173786 bayes_pls_golite062009
transcription regulator activity 1.26775679034218 bayes_pls_golite062009
disulfide oxidoreductase activity 1.14955061683324 bayes_pls_golite062009
DNA binding 0.960359848915972 bayes_pls_golite062009
nucleic acid binding 0.88811762128978 bayes_pls_golite062009
catalytic activity 0.672192331361968 bayes_pls_golite062009
binding 0.618139748326926 bayes_pls_golite062009
maleylacetoacetate isomerase activity 0.426921894831614 bayes_pls_golite062009
oxidoreductase activity 0.314980210547407 bayes_pls_golite062009
protein binding 0.134341907247724 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle