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View Structure Prediction Details

Protein: FBpp0305365, Kr-PA
Organism: Drosophila melanogaster
Length: 502 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0305365, Kr-PA.

Description E-value Query
Range
Subject
Range
gi|73947291 - gi|73947291|ref|XP_541354.2| PREDICTED: similar to Zinc finger protein 606 (Zinc finger protein 328)...
684.0 [0..1] [493..2374]

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Predicted Domain #1
Region A:
Residues: [1-85]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSISMLQDAQ TRTLAAALAG IKQEDVHLDR SMSLSPPMSA NTSATSAAAI YPAMGLQQAA  60
   61 AASAFGMLSP TQLLAANRQA AAFMA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [86-201]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QLPMSTLANT LFPHNPAALF GAWAAQQSLP PQGTHLHSPP ASPHSPLSTP LGSGKHPLNS  60
   61 PNSTPQHHEP AKKARKLSVK KEFQTEISMS VNDMYHTSGG PISPPSSGSS PNSTHD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [202-288]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAGGNAGCVG VSKDPSRDKS FTCKICSRSF GYKHVLQNHE RTHTGEKPFE CPECHKRFTR  60
   61 DHHLKTHMRL HTGEKPYHCS HCDRQFV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.045757
Match: 1tf6A
Description: Transcription factor IIIA, TFIIIA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.70988788192472 bayes_pls_golite062009
nucleic acid binding 4.58713908116892 bayes_pls_golite062009
DNA binding 4.56219307357342 bayes_pls_golite062009
transcription factor activity 3.50954949535763 bayes_pls_golite062009
transcription repressor activity 3.27542149084008 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.22082323675675 bayes_pls_golite062009
binding 3.10743787485868 bayes_pls_golite062009
transcription activator activity 2.19952417915035 bayes_pls_golite062009
chromatin binding 2.18464662431232 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.63161912031789 bayes_pls_golite062009
sequence-specific DNA binding 1.42975942698743 bayes_pls_golite062009
transcription factor binding 1.39608963544799 bayes_pls_golite062009
transcription corepressor activity 1.34049786451995 bayes_pls_golite062009
protein binding 1.00484935878505 bayes_pls_golite062009
transcription cofactor activity 0.77874411480713 bayes_pls_golite062009
catalytic activity 0.245893663605433 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [289-502]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QVANLRRHLR VHTGERPYTC EICDGKFSDS NQLKSHMLVH NGEKPFECER CHMKFRRRHH  60
   61 LMNHKCGIQS PPTPALSPAM SGDYPVAISA IAIEASTNRF AAMCATYGGS NESVDMEKAT 120
  121 PEDDGPLDLS EDGASSVDGH CSNIARRKAQ DIRRVFRLPP PQIPHVPSDM PEQTEPEDLS 180
  181 MHSPRSIGSH EQTDDIDLYD LDDAPASYMG HQQH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 58.39794
Match: 2i13A
Description: No description for 2i13A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle