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View Structure Prediction Details

Protein: Dll-PA
Organism: Drosophila melanogaster
Length: 327 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Dll-PA.

Description E-value Query
Range
Subject
Range
gi|786328 - gi|786328|gb|AAB32671.1| Pax-6 [Rattus sp.]
gi|480038, gi|446399 - gi|480038|pir||S36166 paired box transcription factor Pax-6 - rat (fragment), gi|446399|prf||1911405...
135.0 [0..21] [211..25]

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Predicted Domain #1
Region A:
Residues: [1-104]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDAPDAPHTP KYMDGGNTAA SVTPGINIPG KSAFVELQQH AAAGYGGIRS TYQHFGPQGG  60
   61 QDSGFPSPRS ALGYPFPPMH QNSYSGYHLG SYAPPCASPP KDDF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [105-194]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SISDKCEDSG LRVNGKGKKM RKPRTIYSSL QLQQLNRRFQ RTQYLALPER AELAASLGLT  60
   61 QTQVKIWFQN RRSKYKKMMK AAQGPGTNSG 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.30103
Match: 1b8iA
Description: Ultrabithorax (ubx) homeodomain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 2.82910876106939 bayes_pls_golite062009
DNA binding 2.71139715874068 bayes_pls_golite062009
binding 2.59102816487173 bayes_pls_golite062009
nucleic acid binding 2.4041998404334 bayes_pls_golite062009
transcription factor activity 2.30605638403993 bayes_pls_golite062009
sequence-specific DNA binding 1.81835017168096 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.77114246571754 bayes_pls_golite062009
protein binding 0.853351196918381 bayes_pls_golite062009
transcription activator activity 0.81440394306575 bayes_pls_golite062009
transcription repressor activity 0.77814500281111 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.57338514991304 bayes_pls_golite062009
transcription factor binding 0.22865859991459 bayes_pls_golite062009
chromatin binding 0.203837749053719 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [195-327]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLGGGGPNP GQHSPNQMHS GGNNGGGSNS GSPSHYLPPG HSPTPSSTPV SELSPEFPPT  60
   61 GLSPPTQAPW DQKPHWIDHK PPPQMTPQPP HPAATLHPQT HHHNPPPQMG GYVPQYWYQP 120
  121 ETNPSLVTVW PAV

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.09
Match: 2j63A
Description: No description for 2j63A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle