YRC Public Data Repository - Protein Structure Prediction

Protein:	Pros28.1B-PA, FB...
Organism:	Drosophila melanogaster
Length:	252 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Pros28.1B-PA, FB....

Description	E-value	Query Range	Subject Range
PSA7L_MOUSE - Proteasome subunit alpha type-7-like OS=Mus musculus GN=Psma8 PE=1 SV=1	269.0	[0..1]	[251..1]
PSA_PYRAB - Proteasome subunit alpha OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=psmA PE=3 SV=1 PSMA_PYRAB - Proteasome subunit alpha OS=Pyrococcus abyssi GN=psmA PE=3 SV=1	267.0	[0..3]	[232..8]
PSA_PYRFU - Proteasome subunit alpha OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) GN=p... PSMA_PYRFU - Proteasome subunit alpha OS=Pyrococcus furiosus GN=psmA PE=3 SV=1	266.0	[0..3]	[232..8]
PSA_PYRHO - Proteasome subunit alpha OS=Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC ... PSMA_PYRHO - Proteasome subunit alpha OS=Pyrococcus horikoshii GN=psmA PE=3 SV=1	265.0	[0..3]	[233..8]
gi\|7435881 - pir\|\|D69191 proteasome, alpha subunit - Methanobacterium thermoautotrophicum (strain Delta H) PSA_METTH - Proteasome subunit alpha OS=Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / J...	264.0	[0..2]	[244..6]
gi\|240109415 - gi\|240109415\|gb\|EER27584.1\| proteasome component, putative [Coccidioides posadasii C735 delta SOWgp] gi\|119182842, gi... - gi\|90301311\|gb\|EAS30942.1\| conserved hypothetical protein [Coccidioides immitis RS], gi\|119182842\|re...	263.0	[0..1]	[252..1]
PSMA_METKA - Proteasome subunit alpha OS=Methanopyrus kandleri GN=psmA PE=3 SV=1 PSA_METKA - Proteasome subunit alpha OS=Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938) ...	263.0	[0..5]	[244..10]
PSA7L_MACFA - Proteasome subunit alpha type-7-like OS=Macaca fascicularis GN=PSMA7L PE=2 SV=1	262.0	[0..1]	[233..1]
gi\|116283481 - gi\|116283481\|gb\|AAH14999.1\| PSMA7 protein [Homo sapiens]	261.0	[0..1]	[241..1]
gi\|157820507, gi... - gi\|157820507\|ref\|NP_001102354.1\| hypothetical protein LOC364814 [Rattus norvegicus], gi\|149015674\|gb...	261.0	[0..1]	[235..1]

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Predicted Domain #1

Region A:
Residues: [1-252]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQRYDRAVT IYSPDGHLLQ VEYAQEAVRR GSTVMGLRTN NAIVIGVEKR SVGDLQEERM  60
   61 VRKICMLDDH VVMTFSGLTA DARILVSRAQ MEAQSHRLNF EKPTTVEYIT RYIAQLKQNY 120
  121 TQSNGRRPFG LSCLVGGFDE DGTPHLFQTD PSGIFYEWRA NTTGRSSQPV RDYMEKHADE 180
  181 ILTIADEAAA IKHIVRTLVS VSSLNHTQME VAVLKYRQPL RMIDHQVLAD LERTVRREIE 240
  241 DEAEASRRPR AP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	68.09691
Match:	1iruD
Description:	Proteasome alpha subunit (non-catalytic)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
endopeptidase activity	6.91642761177919	bayes_pls_golite062009
peptidase activity	6.84511694091156	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	6.5973571808298	bayes_pls_golite062009
hydrolase activity	4.47652590304822	bayes_pls_golite062009
threonine-type endopeptidase activity	2.98214579292788	bayes_pls_golite062009
threonine-type peptidase activity	2.98214579292788	bayes_pls_golite062009
binding	1.75265921676176	bayes_pls_golite062009
nucleic acid binding	1.39216781236247	bayes_pls_golite062009
catalytic activity	1.19663085909195	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: