YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: FBpp0310591
Organism: Drosophila melanogaster
Length: 904 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0310591.

Description E-value Query
Range
Subject
Range
HGNC:8794|MIM:60... - 8B
gi|162319354, gi... - gi|162319354|gb|AAI56988.1| Phosphodiesterase 8B [synthetic construct], gi|162317602|gb|AAI56216.1| ...
PDE8B - phosphodiesterase 8B
449.0 [0..23] [893..6]

Back

Predicted Domain #1
Region A:
Residues: [1-132]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIISSQPNLA GSATTTTTTT ISSAHVSQEG TMPLPLPIPV TMPLPNAGTC NCGAVGVGVG  60
   61 VGMGMALGAR QCPSPAVDPT TATATPTSTT PGRDSLTRPA SESELNVGTG TSGTSSSGGN 120
  121 SRPGHRKSSL AL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.39794
Match: 2c2aA
Description: Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [133-366]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ALTPEDEPMD VYQRNLMDLK YPTVLPPNPP LKALLVFHKS DSICEAITAA CQRHQLDVTL  60
   61 VKSKEEALDT LQKSYATAQC YHLIIIDARS SKNLDAEHIA RTIRHTHGHH LTTIIAVCKK 120
  121 SFFEKDDVLI ALLDAGVNRC VAETTNLAMC SVELKQILHS IIRPHNVMST QQALYTALHR 180
  181 LKEVVLITDD LLRIQYANRA TERLLNMRLD EIISKQLEDI FVSDLSTISE QCKN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.39794
Match: 2gwrA
Description: No description for 2gwrA was found.

Predicted Domain #3
Region A:
Residues: [367-424]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IKEFDGILTV RRKSQEGIPM HVRVVPVACI GSAPTHLIFN FDVPGGQMDF IATLPQPK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.08
Match: 2pr5A
Description: No description for 2pr5A was found.

Predicted Domain #4
Region A:
Residues: [425-512]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EAPRGSLHSV RRCSFDVRSI ASDGLRRTSL AKLTSLPLEA PITKIINLLS QVQENCSADE  60
   61 ARLIDKVLEF LKREGLYSPQ MKEIRTDD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [513-904]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PIATDLIGAL LTGPSVYSSR RSSNDSIIRT GSSTRTAAIV PAKMKSNPII MELLDESLSW  60
   61 DFDIFKLEEI TDYHPLLYLG MEMFRRFDVF ATLNIDENVC KAWLAVIEAH YRKSNTYHNS 120
  121 THAADVMQAT GAFITQLTNK DMLVMDRMEE ATALIAAAAH DVDHPGRSSA FLCNSNDALA 180
  181 VLYNDLTVLE NHHAAITFKL TLGDDKINIF KNLDKETYKS ARSTIIDMIL ATEMTRHFEH 240
  241 LAKFVSVFGG EEPRDHNPQT DEETSILMRR MLIKVADVSN PARPMQFCIE WARRIAEEYF 300
  301 MQTDEEKQRH LPIVMPMFDR ATCSIPKSQI GFIEYIIQDM MHAWESFIDM PQLITYMQIN 360
  361 YSQWKKYDEQ GVNTLAEIMA KQPPVGKMAN SK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 96.0
Match: 1oynA
Description: Catalytic domain of cyclic nucleotide phosphodiesterase pde4d
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
3',5'-cyclic-nucleotide phosphodiesterase activity 4.72905094107626 bayes_pls_golite062009
cyclic-nucleotide phosphodiesterase activity 4.61245226349897 bayes_pls_golite062009
phosphoric diester hydrolase activity 3.65984874547256 bayes_pls_golite062009
3',5'-cyclic-AMP phosphodiesterase activity 3.3591603098704 bayes_pls_golite062009
3',5'-cyclic-GMP phosphodiesterase activity 2.96981753811593 bayes_pls_golite062009
hydrolase activity 1.22736412056595 bayes_pls_golite062009
catalytic activity 1.07048165010262 bayes_pls_golite062009
binding 0.994379083280533 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.511207383357891 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.432240759268351 bayes_pls_golite062009
protein binding 0.162314119157812 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle