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View Structure Prediction Details

Protein: CG3499-PB
Organism: Drosophila melanogaster
Length: 736 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG3499-PB.

Description E-value Query
Range
Subject
Range
gi|37528354, gi|... - gi|37528354|ref|NP_931699.1| ATP-dependent metalloprotease [Photorhabdus luminescens subsp. laumondi...
513.0 [0..183] [733..34]

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Predicted Domain #1
Region A:
Residues: [1-101]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSTTTHSVP YLYLGNFSRK PHYYSVNRTK LHGSAGAARL SKSTSTSSRS HDLVLDLRNL  60
   61 LSRSSASIQG MVERAARLNG ILDRRLVDDV LAKVTSMLPS M

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.39794
Match: 2aneA
Description: Crystal structure of N-terminal domain of E.Coli Lon Protease
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.890286795042175 bayes_pls_golite062009
protein binding 0.3997153647519 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [102-290]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RDVRVTLEES ATQIGRVQLQ NYQFEVSLTG AAGSVPTGAN VKVIPTITPG LLRPLFSQQQ  60
   61 LNQIRGFKTD RSIEAEQKRN PTMTSRLKNA LANSPQRLDG DTPLQAEKLR RLLAKSEEHG 120
  121 FNKAESLKIA FAEGYLAAAN SEDSPKSGKT MKYLKTIVVI VVFLGIFLSF FTTSNGSVFR 180
  181 IQLGNQVEV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [291-542]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPEEINVTFE DVKGCDEAKQ ELKEVVEFLK SPEKFSNLGG KLPKGVLLVG PPGTGKTLLA  60
   61 RAVAGEAKVP FFHAAGPEFD EVLVGQGARR VRDLFKAAKA RAPCVIFIDE IDSVGAKRTN 120
  121 SVLHPYANQT INQLLSEMDG FHQNAGVIVL GATNRRDDLD QALLRPGRFD VEVMVSTPDF 180
  181 TGRKEILSLY LTKILHDEID LDMLARGTSG FTGADLENMI NQAALRAAID GAETVSMKHL 240
  241 ETARDKVLMG PE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 73.522879
Match: 1lv7A
Description: AAA domain of cell division protein FtsH
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.77927104644254 bayes_pls_golite062009
protein binding 0.193768631623192 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.191748986931135 bayes_pls_golite062009
pyrophosphatase activity 0.126307266091888 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.106964911545815 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.104838429702897 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [543-593]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RKARLPDEEA NTITAYHEGG HAIVAFYTKE SHPLHKVTIM PRGPSLGHTA Y

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.29
Match: 2di4A
Description: No description for 2di4A was found.

Predicted Domain #5
Region A:
Residues: [594-736]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPEKERYHVT KAQLLAMMDT MMGGRAAEEL VFGTDKITSG ASSDLKQATS IATHMVRDWG  60
   61 MSDKVGLRTI EASKGLGTGD TLGPNTIEAV DAEIKRILSD SYERAKAILR KHTREHKALA 120
  121 EALLKYETLD ADDIKAILNE SQT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 126.0
Match: 2ce7A
Description: EDTA treated
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle