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View Structure Prediction Details

Protein: lox2-PA
Organism: Drosophila melanogaster
Length: 511 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lox2-PA.

Description E-value Query
Range
Subject
Range
gi|55962156, gi|... - gi|55962156|emb|CAI14493.1| deleted in malignant brain tumors 1 [Homo sapiens], gi|55962154|emb|CAI1...
553.0 [0..3] [510..287]

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Predicted Domain #1
Region A:
Residues: [1-172]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCAIEDRKVL KMGLTLVCLT LLAIHMADAV VQHRSLEDAR QERQRLVHRY TKVLNKEEGA  60
   61 IRLVGGDNEY EGNIEVLHNG KWGAVCDDEW DSTEADIVCR QLGFPGMRRY TRSGFFGPAR 120
  121 RRFWMDNLFC EGHEQELVDC HFEGWGENDC EPGEAAGVVC YPPENALIPM AT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.154902
Match: 1by2A
Description: STRUCTURE OF M2BP SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 0.552410974340988 bayes_pls_golite062009
binding 0.536923542644072 bayes_pls_golite062009
catalytic activity 0.43947186099223 bayes_pls_golite062009
receptor activity 0.0495857193797902 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [173-286]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PIIRDEDLPK YPIHSRSRLY VRLRGGRSRI EGRVEVSLDG GRWGSVCADG WSLLEANVVC  60
   61 RQLGLGYASE AFQTDFFGGF NVSRPVLSGS ECYGNETELA DCLHHDASQG IISC

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 5.17
Match: 1by2A
Description: STRUCTURE OF M2BP SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.490715949785074 bayes_pls_golite062009
catalytic activity 0.474271982951055 bayes_pls_golite062009
protein binding 0.471820641297956 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [287-372]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HGNRQHVAAV ICDYIAPDLV VDYLEIEQTA HLEDRPMLLM QCAMEENCVA NEAYQIQRDD  60
   61 PHWRYRSRRL LKFTAAAINA GNADFR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.09691
Match: 2ja4A
Description: No description for 2ja4A was found.

Predicted Domain #4
Region A:
Residues: [373-511]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PFKEKSQWEW HMCHMHFHSM EVFATFDIFN LRGIKVAQGH KASFCLEDSN CLPGVAKKYN  60
   61 CANYGDQGIS INCSDVYLYN LDCQWVDVTD LIPGTYVLKI AINPEFKVAE MNYDNNAAIC 120
  121 DLIYTANFAR VQNCQLGRP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle