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View Structure Prediction Details

Protein: Tbp-PA
Organism: Drosophila melanogaster
Length: 353 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Tbp-PA.

Description E-value Query
Range
Subject
Range
gi|1016266 - gi|1016266|gb|AAA79092.1| TATA-box binding protein
349.0 [0..1] [353..1]

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Predicted Domain #1
Region A:
Residues: [1-145]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDQMLSPNFS IPSIGTPLHQ MEADQQIVAN PVYHPPAVSQ PDSLMPAPGS SSVQHQQQQQ  60
   61 QSDASGGSGL FGHEPSLPLA HKQMQSYQPS ASYQQQQQQQ QLQSQAPGGG GSTPQSMMQP 120
  121 QTPQSMMAHM MPMSERSVGG SGAGG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.0
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [146-353]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGDALSNIHQ TMGPSTPMTP ATPGSADPGI VPQLQNIVST VNLCCKLDLK KIALHARNAE  60
   61 YNPKRFAAVI MRIREPRTTA LIFSSGKMVC TGAKSEDDSR LAARKYARII QKLGFPAKFL 120
  121 DFKIQNMVGS CDVKFPIRLE GLVLTHCNFS SYEPELFPGL IYRMVRPRIV LLIFVSGKVV 180
  181 LTGAKVRQEI YDAFDKIFPI LKKFKKQS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 87.09691
Match: 1rm1A
Description: Structure of a Yeast TFIIA/TBP/TATA-box DNA Complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
general RNA polymerase II transcription factor activity 10.1927670598446 bayes_pls_golite062009
RNA polymerase III transcription factor activity 8.4318102330583 bayes_pls_golite062009
transcription regulator activity 4.66773099672992 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.97397050058114 bayes_pls_golite062009
DNA binding 3.93251147843671 bayes_pls_golite062009
nucleic acid binding 3.82919607287537 bayes_pls_golite062009
RNA polymerase I transcription factor activity 3.24777019705869 bayes_pls_golite062009
binding 2.72886792846471 bayes_pls_golite062009
transcription factor activity 2.38288562794802 bayes_pls_golite062009
protein binding 1.96605926404517 bayes_pls_golite062009
transcription factor binding 1.86204668268867 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.59579825271822 bayes_pls_golite062009
transcription activator activity 1.5285505684695 bayes_pls_golite062009
sequence-specific DNA binding 1.16858275919592 bayes_pls_golite062009
transcription coactivator activity 0.312991469396539 bayes_pls_golite062009
chromatin binding 0.107733889697044 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle