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View Structure Prediction Details

Protein: insc-PA
Organism: Drosophila melanogaster
Length: 859 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for insc-PA.

Description E-value Query
Range
Subject
Range
gi|601948, gi|10... - gi|601948|emb|CAA58175.1| Inscuteable [Drosophila melanogaster], pir||S51646 inscuteable protein - f...
844.0 [0..1] [859..1]

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Predicted Domain #1
Region A:
Residues: [1-249]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFQRSYSKV WWGSEQSSLT SGGFYSSFSG GSSTSSTSNY PQRQPASLGP LGNLSCIQEV  60
   61 EDEQNSSKLS WHKHDSPGSL RSQDSGFSDN EESHQLQHQQ NLSPPSPQSD KQQTPAATPT 120
  121 SVHSVATPPT VVRRVGNSSF YSPLISVTRR ISFTSGQITP KTRSGDEDAE DAELEASRSR 180
  181 LFEQLDSMKL DDGEAEAEED SPPRPAIRRR RRLMRKPMPE PEAASASEEE EVVIAPPPPP 240
  241 PYNNETVYL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [250-398]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEAPPPYNNE TVTFGATEQD ESLQQQPSPL RVRSLRFTAS TSTPKSGSKI AKRGKKHPEP  60
   61 VASWMSEQRW AGEPEVMCTL QHKSIAQEAY KNYTITTSAV CKLVRQLQQQ ALSLQVHFER 120
  121 SERVLSGLQA SSLPEALAGA TQLLSHLDD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [399-447]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FTATLERRGV FFNDAKIERR RYEQHLEQIR TVSKDTRYSL ERQHYINLE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [448-859]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLLDDVQLLK RHTLITLRLI FERLVRVLVI SIEQSQCDLL LRANINMVAT LMNIDYDGFA  60
   61 SLSDAFVQNE AVRTLLVVVL DHKQSSVRAL ALRALATLCC APQAINQLGS CGGIEIVRDI 120
  121 LQVESAGERG AIERREAVSL LAQITAAWHG SEHRVPGLRD CAESLVAGLA ALLQPECCTQ 180
  181 TLLLCAAALN NLSRMEATSH YSIMSNEAIF RLIDTLEHQT CGTSVFLYEQ IVGMLHNMSL 240
  241 NKKCHSHLAN GVIINFITSV YQTEFYQTYG SRAESDAQRR TIKTILHTLT RLASDSPTLG 300
  301 AELLEQWHLP DLLRQSLALK PANSQQQQHL DSSYGGDISQ LARQLLRAHG QEQQLLQATP 360
  361 APGGSFSSGH QTPEAQTQTN SSGMSSSGSK TKAKSSASPL LKFNLTRQES FV

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.05
Match: 2gl7A
Description: No description for 2gl7A was found.

Predicted functions:

Term Confidence Notes
cytoskeletal protein binding 2.83587618361842 bayes_pls_golite062009
actin binding 2.29138393912024 bayes_pls_golite062009
binding 2.17307898957054 bayes_pls_golite062009
protein binding 1.63424405980235 bayes_pls_golite062009
protein transporter activity 1.56169561103687 bayes_pls_golite062009
RNA binding 1.24761758796616 bayes_pls_golite062009
transporter activity 1.08134399163505 bayes_pls_golite062009
substrate-specific transporter activity 0.65168535727044 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle