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View Structure Prediction Details

Protein: Jheh3-PA
Organism: Drosophila melanogaster
Length: 468 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Jheh3-PA.

Description E-value Query
Range
Subject
Range
gi|22001136 - gi|22001136|gb|AAM88329.1|AF517547_1 juvenile hormone epoxide hydrolase III [Drosophila melanogaster...
334.0 [0..1] [468..1]

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Predicted Domain #1
Region A:
Residues: [1-468]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKCLIVFGLI VALFGAFVGY GYVVFTELTK PLPKPEFKDD TYWGPGDAKD FVPDEKIYEF  60
   61 KLQVPQSEID DLRKELNRTL RLTEPLDGIA FEYGFNTYAL EQFVDYWRDN YLTKWDERQE 120
  121 LFNSFKQYKT EIQGLNIHYI HEKVSEEAKE KKHVYPLLLL HGWPGSVREF FDFIPMLTKH 180
  181 SNITDYAFEV VAPSLVGYGW SDAATRPGFN AAEMATVMRN LMLRLGHKKF FIQGGDWGSI 240
  241 IGSNLATLYP ENVIGYHSNM CVLHTPLAIL KGIYGSFFPE KYLPSRFFVD HHFPVWEKWL 300
  301 ELLEESGYFH IQATKPDTIG AALTSSPVGL ASYILEKFQT CTNPGLKQDF GAIVTVFGLE 360
  361 AVLDNLMVYY LTNSATTAAR FYLENVSKTY RDLQLDRVQS PVPMGCARFR FDLASVTDWQ 420
  421 LRDKFPNLTH SMYFQQGSHF AALEMPAMLF NDFTAFVGKI GLHGEKRK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 48.69897
Match: 1qo7A
Description: Bacterial epoxide hydrolase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
juvenile hormone epoxide hydrolase activity 5.69212503305375 bayes_pls_golite062009
epoxide hydrolase activity 4.54228071084398 bayes_pls_golite062009
ether hydrolase activity 3.98161932704074 bayes_pls_golite062009
hydrolase activity, acting on ether bonds 3.22022434415297 bayes_pls_golite062009
hydrolase activity 1.75934962198703 bayes_pls_golite062009
catalytic activity 1.39629727416851 bayes_pls_golite062009
lipase activity 1.27368159234978 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 1.11361651037277 bayes_pls_golite062009
carboxylesterase activity 0.424330502936163 bayes_pls_golite062009
binding 0.140475020321353 bayes_pls_golite062009
palmitoyl-(protein) hydrolase activity 0.0576406065496096 bayes_pls_golite062009
palmitoyl-CoA hydrolase activity 0.00330927487011978 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle