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View Structure Prediction Details

Protein: Jheh1-PA
Organism: Drosophila melanogaster
Length: 474 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Jheh1-PA.

Description E-value Query
Range
Subject
Range
gi|54635849, gi|... - gi|54635849|gb|EAL25252.1| GA13492 [Drosophila pseudoobscura pseudoobscura], gi|125808232|ref|XP_001...
gi|54635849|gb|E... - GA13492-PA [Drosophila pseudoobscura], GA13492 [Drosophila pseudoobscura pseudoobscura]
333.0 [0..1] [474..1]

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Predicted Domain #1
Region A:
Residues: [1-474]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGVTVKILVL ILAIAGGLVY RNVTQLWADL PAPKLDPQEW WGDEAQPKDY EAYLKNNSEV  60
   61 IGNRLSYPDK TIADLKERLN RTLRLTPPLE GVAFEYGFNT NYLKEVVEYW RDDYLPRWRE 120
  121 REVFLWQFNH FTTDIQGLRT HFLHLMVYDD NKVGKKHYPV LLLHGWPGSV REFYDFIHLL 180
  181 HQTNLDNNNK YIFNVVVPSL PGYGWSQGTS RKGLGPAQVA VMMRNLMLRL GYNKFFIQGG 240
  241 DWGSIIGSNI ATLYPENVLG YHSNMCNNLS PKSLAKGLVA EFWPSLFVPS GFEDFFFPKS 300
  301 NEMRYLMEES GYFHIQATKP DTIGAALTDN PVGLAAYILE KFSTWTNPSY RSLPDGGLTK 360
  361 RYKMDALLDN LMIYYLTNSI TTSQRLYAEQ YAQAQRDLHL DRVPTRVPTG CARFKSDIMQ 420
  421 FLDVQLKDKY TNLVHSTYHK KGGHFAALEV PKVLYKDFID FVETVERKFK IKTL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 48.522879
Match: 1qo7A
Description: Bacterial epoxide hydrolase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
juvenile hormone epoxide hydrolase activity 5.69212503305375 bayes_pls_golite062009
epoxide hydrolase activity 4.54228071084398 bayes_pls_golite062009
ether hydrolase activity 3.98161932704074 bayes_pls_golite062009
hydrolase activity, acting on ether bonds 3.22022434415297 bayes_pls_golite062009
hydrolase activity 1.75934962198703 bayes_pls_golite062009
catalytic activity 1.39629727416851 bayes_pls_golite062009
lipase activity 1.27368159234978 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 1.11361651037277 bayes_pls_golite062009
carboxylesterase activity 0.424330502936163 bayes_pls_golite062009
binding 0.140475020321353 bayes_pls_golite062009
palmitoyl-(protein) hydrolase activity 0.0576406065496096 bayes_pls_golite062009
palmitoyl-CoA hydrolase activity 0.00330927487011978 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle