YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: Sema-1b-PC, Sema...
Organism: Drosophila melanogaster
Length: 770 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Sema-1b-PC, Sema....

Description E-value Query
Range
Subject
Range
gi|2852642 - gi|2852642|gb|AAC19159.1| similar to semaphorin-I [Drosophila melanogaster]
691.0 [0..1] [770..1]

Back

Predicted Domain #1
Region A:
Residues: [1-673]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSKSRPSSA AMLVNAIPMI LLITLSGLTI VAGWMPDVKP DLQTKQDKVL AHFIGNSTDY  60
   61 FKILDHNDEF VLVGAKDVIY NVSLNGLKEI ARLEWHSTDA DRELCALKGK HEWDCHNYLR 120
  121 VYALRPNGEV LLCGTNSYKP RCRHYTPVEV SSEEAGSAGH AHAMRYEVSR DVEAQGLCPY 180
  181 SPAHNSTYAF ADGHLYSATV ADFSGGDPLI YRENLRTEQY DLKQLNQPDF VGAIERNGYV 240
  241 LFFFRELSME VMNFGKAVYS RVARVCKNDR GGPYSHGKSW TSFLKARLNC SVPGEFPFYF 300
  301 DEIQAISPIV ESGSKSLIYA VFTTSVNAIP GSAVCAFNVD DILAAFDGEF KSQKDSQSHW 360
  361 LPVEREQVPK PRPGQCVEDS RTLTSIAVNF IKNHPLMEEA VPAVHGRPLL TKVNLHHRLT 420
  421 AIAVHPQVKS LSGAYYDVIY SGTDDGKVTK FINILSTHPN STVDRLKTVV ISEMQVLPLG 480
  481 TPIRELVIST SKNSLVVVSD GSLVSVPLHH CSHIVDCLGC LSLQDPICAW DLQTHECKNL 540
  541 ATSQHKFGTK TYLQSLNSTK KAAALLCPHI PRDAPGAETV SFVTMAPPPT EEQKLLYSNV 600
  601 GSSQGNQPSL EQQPTGGDDF GLNKITLTSM DPDDIMPNLN DPQKSTASVD EIKYASTPSF 660
  661 MLLTTIVFFT FLV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 132.0
Match: 1olzA
Description: The ligand-binding face of the semaphorins revealed by the high resolution crystal structure of SEMA4D
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
antigen binding 3.72597633672466 bayes_pls_golite062009
receptor activity 1.72641278961515 bayes_pls_golite062009
peptide antigen binding 1.66960790017756 bayes_pls_golite062009
binding 1.4212448680573 bayes_pls_golite062009
axon guidance receptor activity 1.25652075776666 bayes_pls_golite062009
transmembrane receptor activity 1.15635912144616 bayes_pls_golite062009
protein binding 1.15274187225647 bayes_pls_golite062009
receptor binding 0.85968680895393 bayes_pls_golite062009
signal transducer activity 0.791510332487796 bayes_pls_golite062009
molecular transducer activity 0.791510332487796 bayes_pls_golite062009
immunoglobulin binding 0.48272957113121 bayes_pls_golite062009
transmembrane receptor protein tyrosine kinase activity 0.31988469097193 bayes_pls_golite062009
MHC class II receptor activity 0.251167772391909 bayes_pls_golite062009
fibroblast growth factor 1 binding 0.15810089914274 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [674-770]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGIAGICCVK AKSRLMEAQM DESHRNHFGK PMQFKHQNTG KDINLLMGSN AYTTTQKTPN  60
   61 LDLEKDRSHE CKNSTEHLEK ELPCKTSTLT KVKRTYI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle