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View Structure Prediction Details

Protein: CG4853-PB, CG4853-PA
Organism: Drosophila melanogaster
Length: 709 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG4853-PB, CG4853-PA.

Description E-value Query
Range
Subject
Range
gi|16768586 - gi|16768586|gb|AAL28512.1| GM09415p [Drosophila melanogaster]
590.0 [0..1] [709..1]

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Predicted Domain #1
Region A:
Residues: [1-85]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDEDILNAVE SLFGKDVKIV DCETSSSLQQ EEVLLVNGVP VKLDGLPADD ASAIKAALLE  60
   61 GQMPSVEHLN QLLFRAGLAQ QPIEV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [86-247]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ETSLTVKSSL TTTEEVLVSR NGQILDERTV ETKENFNHQS HQKEIWHPVK QQSALARATP  60
   61 ENALKYRTTS NSTFASQATD SDERPVDPLG RQLNQTFSNA SLMSSSSAIT GSDQVIGSVS 120
  121 STTIGDKSSN ISSCDSGHDG LFHSVSMSAP WSHPRDTLTD SL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [248-709]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YCDIPSSADE SDAVSILNTH LKITEPFDCQ TAPVYAKDIP KKGNLDSVVN LLINNNTKDL  60
   61 RFAFLTTSRL FSPPHQLLSK IIAKIDNEEE NVLRLLNEWL DTCPGDFSHE LLLQELENKR 120
  121 NVKGLAAFLD GIPQALAQKD ENGRSQLNNL LTKQSSASSL GRQSSIKSLK RFAANVYKTD 180
  181 NVLNNCSSAF ELAHQLYAIE YAYLSQIRLE EFVEILEKDE LKTCISQTKA GTLGSNCISQ 240
  241 VTIDSYVQWF NQLSYLTATE ILKLGKKSQR AQMIDFWVET ALECFNTGNF NSLMAILTAL 300
  301 NLTAIARLKK TWAKVQTTKF EGLEHQMDPS SNFLNYRSTM KAAVWRSERE MANEIERAII 360
  361 PFFSLFLKDL HAINESHETK LANGYINFEK CLHLGTQLRN FGKWQRLDCP YEQLPSVVSY 420
  421 LLKAEVLSED LLMKASYESE PPETGEEKDH YKTLKAARKS NT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 84.39794
Match: 1xdvA
Description: Experimentally Phased Structure of Human the Son of Sevenless protein at 4.1 Ang.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
enzyme regulator activity 1.5659750622955 bayes_pls_golite062009
binding 0.314382910346442 bayes_pls_golite062009
protein binding 0.167385485519274 bayes_pls_golite062009
guanyl-nucleotide exchange factor activity 0.0309302643519621 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle