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View Structure Prediction Details

Protein: gi|7302983, gi|2...
Organism: Drosophila melanogaster
Length: 1173 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7302983, gi|2....

Description E-value Query
Range
Subject
Range
gi|109473951 - gi|109473951|ref|XP_001076882.1| PREDICTED: similar to Leucine-rich repeats and immunoglobulin-like ...
488.0 [0..236] [1081..57]

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Predicted Domain #1
Region A:
Residues: [1-645]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSWSRRRRRN NNNNNNSSSN NNNAASESRS NDNCNYSTTN DFNKINKLLL ITYMLLITAA  60
   61 TICQSAAQSP SSSNGNGVGG SGSTGGSPLS ALLKSGGASY NQQLPQQQLF AMLTRNGGGS 120
  121 SGPRSSGGNR GYTSARQHFM ALSEDYSDAD VDEEDMAALH YPLSASHPPA GVQGSSSSSG 180
  181 ISIQSGSLET NGFVADDGGQ YEHAQKALEA AAAAAKASNK YNIDCPKDCK CLNVLFDCDK 240
  241 LHLERVPVLP SYVQTLHLAN NKLNDTTVLE IRNLLNLTKV SLKRNLLEVI PKFIGLSGLK 300
  301 HLVLANNHIT SISSESLAAL PLLRTLDLSR NKLHTIELNS FPKSNNLVHL ILSFNEITNV 360
  361 NEHSFATLNN LTDLELSNNR LSTLPIRVFK NLNQLKKLAL NFNQLEINWS TFRGLESMKN 420
  421 LQLKSNKIRA LQDGVFYVMH KIETIDLAMN QISSLSRQGL FNLTKLRHLN LSFNAISRIE 480
  481 VDTWEFTQSL EVLDLSNNAI NEFKPQHLDC LHRLKTLNLA HNRLQYLQEN TFDCVKNLEE 540
  541 LNLRRNRLSW IIEDQSAAAP FKGLRKLRRL DLHGNNLKQI STKAMSGLNN LEILNLGSNA 600
  601 LASIQVNAFE HMLRLNKLVF KSLNFICDCD LVWFQQWLKN RFPQQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 54.0
Match: 2a0zA
Description: The molecular structure of toll-like receptor 3 ligand binding domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [646-791]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AEHAVCGYPE HLLDRHLKSL SSSELVCVDS PKPRVEQEPD DMLAVNAANI TLECIASSPT  60
   61 AASLAAADEL KIKWRHDNQH VQERPAVHDG ASTETQIRHD LSTNQTSIYG YLRLTNVTYE 120
  121 SAGRYQCVVS NAFGTTYAQK FKISIG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.0
Match: 2gy5A
Description: No description for 2gy5A was found.

Predicted Domain #3
Region A:
Residues: [792-1173]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IHPTFLQVPS NLTLDAGEMA RLVCSASGDP TPEIALQKFG GSEFPAATER RLQVIREENA  60
   61 FLITNAKPSD SGIYTCTALS AAGEIKVNAT LVVNDKPQPS IPLVHQEVVV GRTCVLQCLS 120
  121 ETANADFELE HPHREWFKEN KPIHISPTAP DGDQLVVVKE NLNWVVLLVG IITVTVICVV 180
  181 VDCCIIWCTL RYQKKKLRMS LAAERHSTQL RPRSLADLGC SYDEANHRRL TVMSTPPSEQ 240
  241 RCLEQGLTLS YLRQTDLEAQ QDHLSSKDSG TGSDAAVKRT LDDFEVAMPS HKHHTDDEEE 300
  301 EEVEEVYEEN EPPYIKHTYE VNYAEPEQHL FLQNNNHNYD GGGIGVAGGV NKMVPNALLR 360
  361 KCSAGASGSN YSSIQQCTTV DI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.221849
Match: 1cs6A
Description: Axonin-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 3.17641566810715 bayes_pls_golite062009
extracellular matrix structural constituent 2.79767000113033 bayes_pls_golite062009
receptor activity 2.05639524829249 bayes_pls_golite062009
molecular transducer activity 1.80932022663119 bayes_pls_golite062009
signal transducer activity 1.80932022663119 bayes_pls_golite062009
fibroblast growth factor 1 binding 1.68957060156689 bayes_pls_golite062009
transmembrane receptor activity 1.65953142725335 bayes_pls_golite062009
antigen binding 1.45942243170397 bayes_pls_golite062009
platelet-derived growth factor receptor binding 1.39941520479711 bayes_pls_golite062009
fibroblast growth factor receptor activity 1.39405837847039 bayes_pls_golite062009
cell adhesion molecule binding 1.36789541796983 bayes_pls_golite062009
protein binding 1.17809977833322 bayes_pls_golite062009
fibroblast growth factor binding 0.940492274094239 bayes_pls_golite062009
receptor binding 0.838643016003073 bayes_pls_golite062009
nucleic acid binding 0.518011841154552 bayes_pls_golite062009
integrin binding 0.32413307774101 bayes_pls_golite062009
transcription regulator activity 0.316848380982695 bayes_pls_golite062009
DNA binding 0.304320681250924 bayes_pls_golite062009
protein kinase activity 0.274138794214258 bayes_pls_golite062009
carbohydrate binding 0.0389714345254086 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle