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View Structure Prediction Details

Protein: Prosbeta1-PA
Organism: Drosophila melanogaster
Length: 224 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Prosbeta1-PA.

Description E-value Query
Range		 Subject
Range
gi|109112866 - gi|109112866|ref|XP_001096870.1| PREDICTED: proteasome (prosome, macropain) subunit, beta type, 6 is...
 201.0 [0..5] [219..24]
PSA4_SPIOL - Proteasome subunit alpha type-4 OS=Spinacia oleracea GN=PAC1 PE=2 SV=1
 201.0 [0..4] [216..20]
gi|65304454 - gi|65304454|emb|CAI76833.1| proteasome subunit, putative [Theileria annulata]
gi|84997473 - gi|84997473|ref|XP_953458.1| proteasome subunit [Theileria annulata strain Ankara]
 201.0 [0..4] [222..20]
PSB6_MOUSE - Proteasome subunit beta type-6 OS=Mus musculus GN=Psmb6 PE=1 SV=3
 200.0 [0..5] [219..23]
gi|68351418 - gi|68351418|gb|EAN32181.1| proteasome subunit alpha type, putative [Theileria parva]
gi|71029642 - gi|71029642|ref|XP_764464.1| proteasome subunit alpha type [Theileria parva strain Muguga]
 200.0 [0..4] [221..20]
PSB6_BOVIN - Proteasome subunit beta type-6 OS=Bos taurus GN=PSMB6 PE=1 SV=1
 199.0 [0..5] [219..24]
PSA4A_ARATH - Proteasome subunit alpha type-4-A OS=Arabidopsis thaliana GN=PAC1 PE=1 SV=1
 198.0 [0..4] [216..20]
PSMB6 - proteasome (prosome, macropain) subunit, beta type, 6
gi|123995447, gi... - gi|60654883|gb|AAX32006.1| proteasome subunit beta type 6 [synthetic construct], gi|60654881|gb|AAX3...
 198.0 [0..5] [219..24]
gi|114665820, gi... - gi|114665820|ref|XP_511290.2| PREDICTED: similar to Proteasome (prosome, macropain) subunit, beta ty...
 198.0 [0..5] [219..24]
PSA_PYRAB - Proteasome subunit alpha OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=psmA PE=3 SV=1
PSMA_PYRAB - Proteasome subunit alpha OS=Pyrococcus abyssi GN=psmA PE=3 SV=1
 198.0 [0..4] [214..25]

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Predicted Domain #1
Region A:
Residues: [1-224] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQPDFDFTDT PVSTGTTIMA VEFDGGVVIG ADSRTSSGAY VANRVTDKLT RITDKVYCCR  60
   61 SGSAADTQAI ADIVAYSLNY HENQTNKDAL VFEAASEFRN YCYSYRESLL AGIIVAGWDE 120
  121 QRGGQVYSIP LGGMLTRESC TIGGSGSSFI YGFVREHYRP NMALEDCVTF VKKAVQHAIY 180
  181 HDGSSGGVVR IGIITKDGIE RRIFYNTESG ASAVSSTPSF ISSE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 48.0
Match: 1iruH
Description: Proteasome beta subunit (catalytic)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
endopeptidase activity 6.91642761177919 bayes_pls_golite062009
peptidase activity 6.84511694091156 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 6.5973571808298 bayes_pls_golite062009
hydrolase activity 4.47652590304822 bayes_pls_golite062009
threonine-type endopeptidase activity 2.98214579292788 bayes_pls_golite062009
threonine-type peptidase activity 2.98214579292788 bayes_pls_golite062009
catalytic activity 1.19663085909195 bayes_pls_golite062009
binding 1.18139971903068 bayes_pls_golite062009
nucleic acid binding 0.448212653390607 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle