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View Structure Prediction Details

Protein: scb-PB
Organism: Drosophila melanogaster
Length: 1115 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for scb-PB.

Description E-value Query
Range
Subject
Range
gi|7511948, gi|2... - pir||T09403 integrin alpha chain Volado-long 1 - fruit fly (Drosophila melanogaster), gi|2827169|gb|...
851.0 [0..1] [1115..1]

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Predicted Domain #1
Region A:
Residues: [1-1115]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNAESTMFPH IFLALLALIS HIEAFNFMPR PSRVINSPKH LKFHINQTRS SYFGYTLVIR  60
   61 QTSIIVGAPR AQSTLESQRT INETGAIYRC SLTNGVCSPY VLDSRGNVDA PYSEYTFDSE 120
  121 RKDFQWLGGS MDGGTKDTDK LLVCAPRFYA PSSRDNHLHG VCYWVNNTVA STPQHVTRIS 180
  181 PLRLKSEQVK EEDNGNKASF FYIMGELGLS AHVADDNTKF LIGAPGINTW RGSVILYRQV 240
  241 DPVDNPTASR RDTSKALRRT YRDVDSNDYT PEHYAPEIPT PGLWGQEEDS YFGYAVSSGF 300
  301 FDSSNPTKLL YVATAPQANK QSGEAYIFDV RGKSIHKYHV FRGEQFGEYF GYSVLAEDLN 360
  361 GDGKTDVIVS APQHALEDSH DNGAIYVFIN KGFFNFERQI LRSPVETMAR FGTALSRLGD 420
  421 INHDGYNDVA VGAPFAGNGT VFIYLGSENG LRDQPSQRLD APSQQPSKYG SHMFGHGLSR 480
  481 GSDIDGNGFN DFAIGAPNAE AVYLYRAYPV VKVHATVKSE SREIKPEQEK VKITACYRLS 540
  541 TTSTDKLVQE QELAIRIAMD KQLKRVKFTQ TQTNEISFKV NANFGEQCRD FETQVRYSEK 600
  601 DIFTPIDLEM HYELTKKVPD SEEFCETCAI VDPTEPKVST QNIIFSTGCA TDVCTADLQL 660
  661 RSKDVSPTYI LGSADTLRLN YEITNIGETA YLPQFNVTST SRLAFAQVPG NCKVVDAVMV 720
  721 CDLNRGRPLA KGDTDSVTIS FDVSQLSGQS LIIHAEVFST GYEQNPTDNR QTNVIGLKEF 780
  781 TEIDASGGQT NSQIDLEHYS NSAEIVNNYE IKSNGPSVIE QLTVSFYIPI AYKVAGSTAI 840
  841 IPIINVTSLK MQASYDSQLL SIDLYDQNNT MLVVDPVEVT TTLSGGLERT VITQNRQSYD 900
  901 IHTSGHVHQT MEVLDTSMVA TASMSRKRRD LKALTANREQ YARISNVKAH DLLSDDFKGK 960
  961 LPVNRTIVFN CRDPEMTICV RAEMRVHFRP EKSINLNMRY SVDLNEVNAI LVDPWEYFVI1020
 1021 LTDLKLQKKG DPTSTSFSIN RRIEPNIISK HQETGLPIWI IIVSVIGGLL LLSAISYLLY1080
 1081 KFGFFNRTKK DELDRLVQQN PVEPEAENLN SGGNN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 173.0
Match: 1jv2A
Description: Thigh, calf-1 and calf-2 domains of integrin alpha; Integrin alpha N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cell adhesion molecule binding 4.38909417354069 bayes_pls_golite062009
receptor activity 3.07436728891089 bayes_pls_golite062009
protein binding 2.93314130654223 bayes_pls_golite062009
binding 2.38505574840555 bayes_pls_golite062009
signal transducer activity 2.30570215634503 bayes_pls_golite062009
molecular transducer activity 2.30570215634503 bayes_pls_golite062009
extracellular matrix binding 2.29992000538847 bayes_pls_golite062009
fibronectin binding 2.1460818503023 bayes_pls_golite062009
transmembrane receptor activity 1.89652634417708 bayes_pls_golite062009
integrin binding 1.46467851042106 bayes_pls_golite062009
laminin receptor activity 0.57752974249266 bayes_pls_golite062009
protein complex binding 0.317709418149211 bayes_pls_golite062009
receptor binding 0.272415627526009 bayes_pls_golite062009
laminin binding 0.0766626920324303 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle