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View Structure Prediction Details

Protein: cid-PA
Organism: Drosophila melanogaster
Length: 225 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cid-PA.

Description E-value Query
Range
Subject
Range
gi|32345668 - gi|32345668|gb|AAM80988.1| centromeric histone H3-like protein Cid [Drosophila melanogaster]
253.0 [0..1] [225..1]

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Predicted Domain #1
Region A:
Residues: [1-87]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPRHSRAKRA PRPSANNSKS PNDDDTAFRS PEPEDGTDYG LEFTTSQLTL QDNNRRSSTL  60
   61 RRDAGRRQPA ARDSSTSGEE EDQENRY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [88-225]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTTRSPQTRR MTVQQESKTR AAGPVAAQNQ TRRRKAANPM SRAKRMDREI RRLQHHPGTL  60
   61 IPKLPFSRLV REFIVKYSDD EPLRVTEGAL LAMQESCEMY LTQRLADSYM LTKHRNRVTL 120
  121 EVRDMALMAY ICDRGRQF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.045757
Match: 1u35A
Description: Crystal structure of the nucleosome core particle containing the histone domain of macroH2A
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
general RNA polymerase II transcription factor activity 3.77402874003635 bayes_pls_golite062009
binding 3.12722734218139 bayes_pls_golite062009
centromeric DNA binding 2.60445660474495 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.17470289921427 bayes_pls_golite062009
DNA binding 1.81202026929492 bayes_pls_golite062009
nucleic acid binding 1.77431079461635 bayes_pls_golite062009
transcription factor binding 1.49909125565453 bayes_pls_golite062009
transcription cofactor activity 1.37016786211811 bayes_pls_golite062009
protein binding 1.2861218811362 bayes_pls_golite062009
transcription regulator activity 1.07001118921201 bayes_pls_golite062009
transcription coactivator activity 0.483720456107869 bayes_pls_golite062009
transcription repressor activity 0.38665562690801 bayes_pls_golite062009
histone acetyltransferase activity 0.322861678821436 bayes_pls_golite062009
lysine N-acetyltransferase activity 0.322861678821436 bayes_pls_golite062009
histone binding 0.218942897869955 bayes_pls_golite062009
transcription corepressor activity 0.0581806902793005 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle