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View Structure Prediction Details

Protein: NAT1-PA, NAT1-PB
Organism: Drosophila melanogaster
Length: 918 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NAT1-PA, NAT1-PB.

Description E-value Query
Range
Subject
Range
gi|28380948 - gi|28380948|gb|AAO41441.1| RE34257p [Drosophila melanogaster]
652.0 [0..1] [918..1]

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Predicted Domain #1
Region A:
Residues: [1-153]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYAQLCKRLS EEAPSFDKEP SNSSTFLRLL IAVCRDKFNN RLKRDENDNR PPPENEADEE  60
   61 ERRHLAKQRM LGNVKFIGEL NKLDMLSKNV LHQCIMELFD KKKKRTAGTQ EMCEDMECLA 120
  121 QLLKTCGKNL DSEQGKELMN QYFEKLERRS KSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 66.39794
Match: 1hu3A
Description: Eukaryotic initiation factor eIF4G
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA cap binding 3.2160251815809 bayes_pls_golite062009
binding 1.99013774955562 bayes_pls_golite062009
protein binding 1.75981610748679 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [154-579]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EYPPRIRFML KDVIELRQNN WVPRKLGTTE GPVPIKQIRS DDDSIIRTPF PNRNRDMRNN  60
   61 DRDSDSWMNR FHLNIQPGGY NDMFSGLSVT GASPIVSPFA TSNRDRDRDN RQYNNRGDRN 120
  121 RDRDQGGSGG ANYGNRYNKH NQNGGGSGGG SSNNRDRDDS RRNNDRDRDR NDGQYGGNQL 180
  181 LGSKELAPRF KRNLITTNQD AVENLQMRPA ANSLLFRAAS QNQKFPATLP MSTPPNSSGS 240
  241 NNQGSSQGQL SNSHYPMLGT PTSHLINPTR PSSTPSAEYA DNRTLLGVQQ ERGLKATSSS 300
  301 PNFSSGAEKL DLDGQAGRKG SHDGKDQGKN GSVERPSTPA GGIGSAKQQK KDKGPNKEEL 360
  361 SKKASQYFKD RFYYDEEEDA EVTEIEIKDI DETKTEEADA APVEVSEVKE DAAIPVTTPD 420
  421 RFTKLV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.522879
Match: 1y0fB
Description: No description for 1y0fB was found.

Predicted Domain #3
Region A:
Residues: [580-918]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGFLELKLPE KALKDVCINL LMEVLDRVND VFLERAVRLL QTLRKQSNIK PNIVVEIFKQ  60
   61 VVNKMNEREA LNPRIVSLVA SLLAKTICEP ALLKLSDIAN FTDNGQHYPL FLLVLQQLVK 120
  121 VIGKDALEEK FRASKVDLMN SLPEADRNKE RLAGILEDRK LSFLYPLLKV QAEMLKQLQS 180
  181 DPNPNNFYKW IKANVDNKYY KDPGFIQALM TVVVKYVTKE TTLADNLDPK EHPEKSVTQK 240
  241 EQQLLENYSQ MLQTFLGQNE LQLMALYALQ TFCYNENFPK GMLCRWFKYL YESEIIEEEA 300
  301 FVLWKEEISD KYPGKGSALF QVNAWLTWLQ EAESEDDED

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 101.0
Match: 1ug3A
Description: C-terminal portion of human eIF4GI
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle