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View Structure Prediction Details

Protein: Pimet-PA
Organism: Drosophila melanogaster
Length: 391 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Pimet-PA.

Description E-value Query
Range
Subject
Range
gi|54635263, gi|... - gi|54635263|gb|EAL24666.1| GA11585-PA [Drosophila pseudoobscura], gi|125806618|ref|XP_001360092.1| G...
234.0 [0..1] [382..1]

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Predicted Domain #1
Region A:
Residues: [1-275]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSHKFICGS LTKMTETGIT FDPPVYEQRY CATIQILEDA RWKDQIKKVV EFGCAEMRFF  60
   61 QLMRRIETIE HIGLVDIDKS LLMRNLTSVN PLVSDYIRSR ASPLKVQILQ GNVADSSEEL 120
  121 RDTDAVIAIE LIEHVYDDVL AKIPVNIFGF MQPKLVVFST PNSDFNVIFT RFNPLLPNGF 180
  181 RHEDHKFEWS RDEFKNWCLG IVEKYPNYMF SLTGVGNPPK EYESVGPVSQ IAIFVRKDML 240
  241 EMQLVNPLVS KPNIDKESIP YKLIHTVEYP FYVDT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.69897
Match: 1vl5A
Description: Crystal structure of hypothetical protein (BH2331) from Bacillus halodurans at 1.95 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
methyltransferase activity 4.64500705012502 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 4.57389022626587 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 3.74830027382001 bayes_pls_golite062009
RNA methyltransferase activity 3.6174490060285 bayes_pls_golite062009
N-methyltransferase activity 3.00112136063228 bayes_pls_golite062009
rRNA methyltransferase activity 2.80578045927127 bayes_pls_golite062009
protein methyltransferase activity 2.74535979387581 bayes_pls_golite062009
transferase activity 2.42370637689376 bayes_pls_golite062009
DNA-methyltransferase activity 1.8182614465692 bayes_pls_golite062009
catalytic activity 1.62377578202456 bayes_pls_golite062009
histone methyltransferase activity 1.42140847541194 bayes_pls_golite062009
arginine N-methyltransferase activity 1.40233857644962 bayes_pls_golite062009
protein-arginine N-methyltransferase activity 1.40233857644962 bayes_pls_golite062009
tRNA methyltransferase activity 1.32437128142157 bayes_pls_golite062009
site-specific DNA-methyltransferase (adenine-specific) activity 0.88654745691593 bayes_pls_golite062009
rRNA (uridine) methyltransferase activity 0.75904932606473 bayes_pls_golite062009
rRNA (adenine) methyltransferase activity 0.72946673557525 bayes_pls_golite062009
histone-arginine N-methyltransferase activity 0.67380437956274 bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity 0.62885479399246 bayes_pls_golite062009
protein-arginine omega-N monomethyltransferase activity 0.355464145533041 bayes_pls_golite062009
rRNA (cytosine) methyltransferase activity 0.346042596102079 bayes_pls_golite062009
O-methyltransferase activity 0.32686871890222 bayes_pls_golite062009
binding 0.207713650201315 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [276-391]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RTEKEKLWTE VQIELQRFKR QFESSEIEEG TYQDTCNMPI AFLLDRLEHV GATKERIEEL  60
   61 LLENNLTVEN ECVLIVSSDQ ESEWSDPYKF SDRSSQDDAL VDQEQEEERW DQGPES

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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