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View Structure Prediction Details

Protein: Damm-PA
Organism: Drosophila melanogaster
Length: 255 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Damm-PA.

Description E-value Query
Range
Subject
Range
gi|114632892 - gi|114632892|ref|XP_508043.2| PREDICTED: similar to Lice2 beta cysteine protease isoform 2 [Pan trog...
250.0 [0..3] [249..69]

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Predicted Domain #1
Region A:
Residues: [1-255]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYLPERTEHQ KIERLYDSNR VNAEPGQGLD LNEKLKPPAV YILNHEQFPQ DSQLNRKGSS  60
   61 NDVNALRKTF ESLKCRVEVI SNPALPDVKN KVKEWSAKRF TQDAGFVLFI LSHGDRKEKI 120
  121 LACDHREYHL DDDVLFPLFR NPTLSGKPKI LIVQACKGPL RADAKKMNNE PYIKCYSCSE 180
  181 GYLSYRNENH GSVFIQTLCE AMDQYGLTRD FQSIFKHVKA EVERRSTMTG SKQVPSEESH 240
  241 NFDKPFYFGN YAKNT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 65.522879
Match: 1i4oA
Description: Caspase-7
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 3.24815349282067 bayes_pls_golite062009
protein binding 2.96725373477762 bayes_pls_golite062009
binding 2.91261616137775 bayes_pls_golite062009
cyclin-dependent protein kinase regulator activity 2.60103365510479 bayes_pls_golite062009
hydrolase activity 2.45602706385958 bayes_pls_golite062009
cysteine-type peptidase activity 2.37850336421322 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 2.07426831021634 bayes_pls_golite062009
cysteine-type endopeptidase activity 1.82979469421101 bayes_pls_golite062009
endopeptidase activity 1.58137850574981 bayes_pls_golite062009
cyclin-dependent protein kinase inhibitor activity 1.38256499817012 bayes_pls_golite062009
catalytic activity 1.03907950272772 bayes_pls_golite062009
enzyme regulator activity 0.0737251792690711 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle