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View Structure Prediction Details

Protein: Updo-PA
Organism: Drosophila melanogaster
Length: 356 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Updo-PA.

Description E-value Query
Range
Subject
Range
DCUP_PSEHT - Uroporphyrinogen decarboxylase OS=Pseudoalteromonas haloplanktis (strain TAC 125) GN=hemE PE=3 SV=1
477.0 [0..9] [355..3]

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Predicted Domain #1
Region A:
Residues: [1-356]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKDAKPFPVL KNDNLLRAAR GEVVDRVPVW VMRQAGRYLP EFQELRKHHD FFTVCRTPEL  60
   61 ACEVTMQPLR RFDLDASIIF SDILVIPQAL GLTVEMHAGV GPVLPQPIVV PEDLKRLTPD 120
  121 GALSRLSYVG DAITMMRHKL EGRVPLIGFT GAPWTLMGYM IEGGGSKTMS KAKAWLNEHP 180
  181 EDSKLFLNLL TDAIVDYLEM QVKAGAQMLQ VFESSAEHLS KEQFLQWCVP YLKRIRDELV 240
  241 DRLTKKAIPV VPMTLFAKGA GHSLKEQSEL GYDVIGLDWT VDPLEARNLV GPNITLQGNL 300
  301 DPQDMYRDPD ELRNLTTEMV HKFGKSRYIA NLGHGITPQT PITSMEVLVE AVHKAL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 129.0
Match: 1r3qA
Description: Uroporphyrinogen Decarboxylase in complex with coproporphyrinogen-I
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
uroporphyrinogen decarboxylase activity 4.48282084722609 bayes_pls_golite062009
catalytic activity 2.37862248560593 bayes_pls_golite062009
carboxy-lyase activity 1.67493268854029 bayes_pls_golite062009
carbon-carbon lyase activity 1.54242506764415 bayes_pls_golite062009
binding 1.19577203030346 bayes_pls_golite062009
transferase activity 1.11861612545715 bayes_pls_golite062009
protein binding 0.30230496242508 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle