| Protein: | Optix-PA |
| Organism: | Drosophila melanogaster |
| Length: | 487 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Optix-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
222.0 | [0..29] | [223..1] |
|
Region A: Residues: [1-129] |
1 11 21 31 41 51
| | | | | |
1 MAVGPTEGKQ PPSESFSPTH HQIIAPSPIL AVPTLAFSAA QVEIVCKTLE DSGDIERLAR 60
61 FLWSLPVALP NMHEILNCEA VLRARAVVAY HVGNFRELYA IIENHKFTKA SYGKLQAMWL 120
121 EAHYIEAEK
|
| Detection Method: |  |
| Confidence: | 22.154902 |
| Match: | 1rutX |
| Description: | Complex of LMO4 LIM domains 1 and 2 with the ldb1 LID domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 4.00967542385368 | bayes_pls_golite062009 |
| DNA binding | 3.60745514727532 | bayes_pls_golite062009 |
| nucleic acid binding | 3.16757861573985 | bayes_pls_golite062009 |
| binding | 2.96409924710655 | bayes_pls_golite062009 |
| transcription factor activity | 2.90769972671972 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 1.62841402245495 | bayes_pls_golite062009 |
| transcription activator activity | 1.62405765585032 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 1.50210964370113 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 1.49515149729803 | bayes_pls_golite062009 |
| protein binding | 1.39455913713025 | bayes_pls_golite062009 |
| transcription factor binding | 1.38523780690867 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 0.68270103300828 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.58115018700114 | bayes_pls_golite062009 |
| transcription repressor activity | 0.256420113528322 | bayes_pls_golite062009 |
| catalytic activity | 0.101795606736461 | bayes_pls_golite062009 |
|
Region A: Residues: [130-224] |
1 11 21 31 41 51
| | | | | |
1 LRGRSLGPVD KYRVRKKFPL PPTIWDGEQK THCFKERTRS LLREWYLQDP YPNPTKKREL 60
61 AKATGLNPTQ VGNWFKNRRQ RDRAAAAKNR IQHSQ
|
| Detection Method: | |
| Confidence: | 15.30103 |
| Match: | 1fjlA |
| Description: | Paired protein |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.13863038737912 | bayes_pls_golite062009 |
| DNA binding | 4.66369707598026 | bayes_pls_golite062009 |
| nucleic acid binding | 4.20953772435302 | bayes_pls_golite062009 |
| transcription factor activity | 4.06706589695599 | bayes_pls_golite062009 |
| binding | 3.02779747447702 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.41271657675151 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.26183812259792 | bayes_pls_golite062009 |
| transcription repressor activity | 1.91962622287073 | bayes_pls_golite062009 |
| transcription activator activity | 1.77700860354597 | bayes_pls_golite062009 |
| transcription factor binding | 1.40653841901929 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.14886080629275 | bayes_pls_golite062009 |
| chromatin binding | 0.876241359231159 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.84983974758882 | bayes_pls_golite062009 |
| protein binding | 0.830419844171551 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.25931464844298 | bayes_pls_golite062009 |
|
Region A: Residues: [225-387] |
1 11 21 31 41 51
| | | | | |
1 NSSGMGCRSR RADGAASPTP SDSSDSDISL GTHSPVPSSL QLQHSPGSTS NGANDREESL 60
61 SVDDDKPRDL SGSLPLPLSL PLPLASPTHT PPQLPPGYGG GAGAGPGGPL TGPGCLPPFK 120
121 LDAATSLFSA GCYLQSFSNL KEMSQQFPIQ PIVLRPHPQL PQS
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [388-487] |
1 11 21 31 41 51
| | | | | |
1 LALNGASGGP PLHHPAYAAA YSVECVPGGH GPPHPPPKLR INSPEKLNST AVAAAASVGG 60
61 GGGNQHHEPT TTGYHHSGQL MLHRPFSTSP ELKHSAPEIT
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
