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View Structure Prediction Details

Protein: Hey-PA
Organism: Drosophila melanogaster
Length: 425 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Hey-PA.

Description E-value Query
Range
Subject
Range
gi|115646541 - gi|115646541|gb|ABJ17078.1| RT01017p [Drosophila melanogaster]
212.0 [0..1] [425..1]

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Predicted Domain #1
Region A:
Residues: [1-81]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDHNMHVNAP SLHHWGYAAG PGVVMPGATA TTPQSHWVPP PQSHHSAHSN HSHGHSQGHS  60
   61 HGIGSLKRTL SESDCDDLYS E

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [82-163]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESSKEQISPS EPGSCQLMSR KKRRGVIEKK RRDRINSSLT ELKRLVPSAY EKQGSAKLEK  60
   61 AEILQLTVEH LKSLQSKTLD SL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.221849
Match: 1an4A
Description: Usf B/HLH domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.12507195426228 bayes_pls_golite062009
nucleic acid binding 0.43204604575196 bayes_pls_golite062009
DNA binding 0.40884226851256 bayes_pls_golite062009
transcription regulator activity 0.31759335140578 bayes_pls_golite062009
transcription factor activity 0.09721565916723 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [164-204]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SYDPQRVAMD YHIIGFRECA AEVARYLVTI EGMDIQDPLR L

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.0
Match: 2db7A
Description: No description for 2db7A was found.

Predicted functions:

Term Confidence Notes
binding 0.533405820900955 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [205-425]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RLMSHLQYFV QQRELSAKSC ASPGGWSPAA PSSSGYQPNC AAAPYQSYAA PANPGAYVSS  60
   61 YPTLSASPSQ QAQQLGGRTS VSRTSGSAVT ESLPSHDLHS DSSSQQQQQQ QQQQQQQQQH 120
  121 QQQQHQQQQQ RTQTTPQPTQ QQHYTHDHSA VHSEQQVPTY IELTNSNRPA AIGSDSLSYS 180
  181 AAPQYPVSGL PGQDYNNSSV LQYATPNGAK PYRPWGAEMA Y

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.15
Match: 2j63A
Description: No description for 2j63A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle