YRC Public Data Repository - Protein Structure Prediction

Protein:	CG1707-PA
Organism:	Drosophila melanogaster
Length:	176 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG1707-PA.

Description	E-value	Query Range	Subject Range
gi\|50740506 - gi\|50740506\|ref\|XP_419481.1\| PREDICTED: similar to Glyoxylase 1 [Gallus gallus]	169.0	[0..1]	[176..1]
LGUL_RAT - Lactoylglutathione lyase OS=Rattus norvegicus GN=Glo1 PE=1 SV=3	165.0	[0..5]	[176..9]
gi\|31981282, gi\|... - gi\|31981282\|ref\|NP_079650.2\| glyoxalase 1 [Mus musculus], gi\|19354350\|gb\|AAH24663.1\| Glyoxalase 1 [M...	163.0	[0..5]	[173..9]
gi\|114607262 - gi\|114607262\|ref\|XP_001173775.1\| PREDICTED: glyoxalase I isoform 5 [Pan troglodytes]	163.0	[0..5]	[176..9]
LGUL_MACFA - Lactoylglutathione lyase OS=Macaca fascicularis GN=GLO1 PE=2 SV=3 gi\|109071018 - gi\|109071018\|ref\|XP_001117098.1\| PREDICTED: glyoxalase I [Macaca mulatta]	162.0	[0..5]	[176..9]
gi\|183258, gi\|50... - gi\|5729842\|ref\|NP_006699.1\| glyoxalase I [Homo sapiens], gi\|5020074\|gb\|AAD38008.1\|AF146651_1 glyoxal...	162.0	[0..5]	[176..9]
gi\|61367882, gi\|... - gi\|61367890\|gb\|AAX43062.1\| glyoxalase I [synthetic construct], gi\|61367882\|gb\|AAX43061.1\| glyoxalase...	162.0	[0..5]	[176..9]

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Predicted Domain #1

Region A:
Residues: [1-176]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGDVTGLSNA QADELCQKPD SSTKDFLFQQ TMYRIKDPRK SLPFYTGVLG MTLLVKLDFP  60
   61 EAKFSLYFLG YENATDVPKD PKQRRSWALS RKATIELTHN WGTERDPDQN YHTGNTDPRG 120
  121 FGHIGIMVPD VYAACQRFQE LGVDFVKKPD DGRMKGLAFI KDPDGYWIEI FNAHSV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	40.154902
Match:	1froA
Description:	Glyoxalase I (lactoylglutathione lyase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
lactoylglutathione lyase activity	3.91334658149719	bayes_pls_golite062009
carbon-sulfur lyase activity	1.44168339433372	bayes_pls_golite062009
catalytic activity	1.21778090213032	bayes_pls_golite062009
binding	1.0454158969791	bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	0.397354910065381	bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	0.343093696737896	bayes_pls_golite062009
protein binding	0.28912087714501	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: