YRC Public Data Repository - Protein Structure Prediction

Protein:	Gadd45-PA
Organism:	Drosophila melanogaster
Length:	163 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Gadd45-PA.

Description	E-value	Query Range	Subject Range
gi\|114609445 - gi\|114609445\|ref\|XP_001155941.1\| PREDICTED: similar to 40S ribosomal protein S12 [Pan troglodytes]	198.0	[0..23]	[142..228]
gi\|148231845, gi... - gi\|27881763\|gb\|AAH44028.1\| Rps12-prov protein [Xenopus laevis], gi\|148231845\|ref\|NP_001080594.1\| rib... gi\|51258906, gi\|... - gi\|89272933\|emb\|CAJ82890.1\| ribosomal protein S12 [Xenopus tropicalis], gi\|56605872\|ref\|NP_001008435...	179.0	[0..20]	[149..3]
gi\|219500954, gi... - gi\|219500954\|ref\|XP_002246877.1\| hypothetical protein BRAFLDRAFT_109012 [Branchiostoma floridae], gi... gi\|18845074 - gi\|18845074\|gb\|AAL79538.1\|AF470687_1 40S ribosomal protein S12 [Branchiostoma belcheri]	179.0	[0..20]	[149..3]
gi\|147905512, gi... - gi\|34785258\|gb\|AAH56655.1\| MGC68529 protein [Xenopus laevis], gi\|147905512\|ref\|NP_001079902.1\| ribos...	179.0	[0..20]	[142..3]
gi\|60654351 - gi\|60654351\|gb\|AAX29866.1\| ribosomal protein S12 [synthetic construct]	178.0	[0..20]	[142..3]
gi\|109088312, gi... - gi\|109088312\|ref\|XP_001090940.1\| PREDICTED: similar to ribosomal protein S12 isoform 3 [Macaca mulat...	178.0	[0..20]	[142..3]
RPS12 - ribosomal protein S12 tr\|G1SFR8\|G1SFR8... - pep:novel chromosome:oryCun2:12:123075000:123077422:1 gene:ENSOCUG00000001606 transcript:ENSOCUT0000... gi\|1085435 - pir\|\|JC4159 ribosomal protein S12 - pig RS12_BOVIN - 40S ribosomal protein S12 OS=Bos taurus GN=RPS12 PE=2 SV=1 RS12_PIG - 40S ribosomal protein S12 OS=Sus scrofa GN=RPS12 PE=2 SV=2 gi\|149032886, gi... - gi\|78126139\|ref\|NP_113897.2\| ribosomal protein S12 [Rattus norvegicus], gi\|34849622\|gb\|AAH58460.1\| R... gi\|55627400 - gi\|55627400\|ref\|XP_518748.1\| PREDICTED: similar to ribosomal protein S12 [Pan troglodytes] gi\|40254577 - ref\|NP_035425.2\| ribosomal protein S12 [Mus musculus] ENSCJAT00000005492 - null gi\|109082720, gi... - gi\|109082724\|ref\|XP_001094552.1\| PREDICTED: similar to ribosomal protein S12 isoform 3 [Macaca mulat... gi\|126310576 - gi\|126310576\|ref\|XP_001369942.1\| PREDICTED: similar to 40S ribosomal protein S12 [Monodelphis domest... gi\|149722961 - gi\|149722961\|ref\|XP_001504406.1\| PREDICTED: ribosomal protein S12 [Equus caballus] gi\|61363690, gi\|... - gi\|61363697\|gb\|AAX42430.1\| ribosomal protein S12 [synthetic construct], gi\|61363690\|gb\|AAX42429.1\| r... gi\|74141830, gi\|... - gi\|94406873\|ref\|XP_992944.1\| PREDICTED: similar to ribosomal protein S12 [Mus musculus], gi\|94382274... gi\|73945533, gi\|... - gi\|73945535\|ref\|XP_859516.1\| PREDICTED: similar to ribosomal protein S12 isoform 7 [Canis familiaris...	178.0	[0..20]	[142..3]
RS12_CHICK - 40S ribosomal protein S12 OS=Gallus gallus GN=RPS12 PE=1 SV=2	177.0	[0..20]	[142..3]
gi\|45504877, gi\|... - gi\|68402572\|ref\|XP_687451.1\| PREDICTED: similar to ribosomal protein S12 [Danio rerio], gi\|45504877\|... gi\|156914875, gi... - gi\|160420153\|ref\|NP_001104194.1\| hypothetical protein LOC100126614 [Xenopus laevis], gi\|156914875\|gb...	177.0	[0..20]	[149..3]
gi\|149250091, gi... - gi\|94368670\|ref\|XP_988610.1\| PREDICTED: similar to ribosomal protein S12 [Mus musculus], gi\|14925009...	176.0	[0..20]	[142..3]

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Predicted Domain #1

Region A:
Residues: [1-163]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVVEENCSMH HLERELDLEL EIDMAMECAP IGRTIKSALL RAQSEARVIV GLSAAINVLS  60
   61 KSPEGSLFCL MAQPKDGDSA THMHEVLLEA FCYENDIYVI KVDDATKLSR ILGQDSVESC 120
  121 CLVQKVWADA PEEQLTKAEN QLVDYCEAHW DAPQQPIVQL PAV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	10.0
Match:	1rlgA
Description:	Molecular basis of Box C/D RNA-protein interaction: co-crystal structure of the Archaeal sRNP intiation complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.34187530323842	bayes_pls_golite062009
nucleic acid binding	1.75603194702351	bayes_pls_golite062009
protein binding	0.381324299701367	bayes_pls_golite062009
RNA binding	0.359317669023596	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: