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View Structure Prediction Details

Protein: gi|21645125, gi|...
Organism: Drosophila melanogaster
Length: 393 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|21645125, gi|....

Description E-value Query
Range
Subject
Range
gi|58385904, gi|... - gi|58385904|ref|XP_314296.2| ENSANGP00000013151 [Anopheles gambiae str. PEST], gi|55240252|gb|EAA097...
455.0 [0..1] [381..1]

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Predicted Domain #1
Region A:
Residues: [1-140]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVNVYSTNV TSENLSRHDM LAWVNDCLQS QFSKIEELCT GAAYCQFMDM LFPNSVPVKR  60
   61 VKFRTNLEHE YIQNFKILQA GFKKMSVDKI IPVDKLIKGR FQDNFEFLQW FKKFFDANYD 120
  121 GREYDPVAQR GGVKLGNGNG 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 76.0
Match: 1wyoA
Description: Solution structure of the CH domain of human microtubule-associated protein RP/EB family member 3
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [141-272]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HGSNGGSGVG SSNNDLHLMH RRPLQAPASG GRMPARVIAS TGTVLSKLRT PIIPIDKLVK  60
   61 GRFQDNFEFL QWFKKFFDAN YDGRDYDASA VREGAPMGFG SGAVKSLPGT AASGVSSSYR 120
  121 RGPSATTRPA MT

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 5.09
Match: 1vkaA
Description: Southeast Collaboratory for Structural Genomics: Hypothetical Human Protein Q15691 N-Terminal Fragment
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cytoskeletal protein binding 6.0562477479739 bayes_pls_golite062009
microtubule plus-end binding 5.72370607907493 bayes_pls_golite062009
microtubule binding 5.63808442303747 bayes_pls_golite062009
tubulin binding 5.63161872515663 bayes_pls_golite062009
actin binding 5.4843525466095 bayes_pls_golite062009
actin filament binding 3.58546515893973 bayes_pls_golite062009
binding 2.73681134719616 bayes_pls_golite062009
structural constituent of cytoskeleton 2.33067686982903 bayes_pls_golite062009
protein binding 2.17650965264372 bayes_pls_golite062009
structural molecule activity 0.952313983641982 bayes_pls_golite062009
dynein binding 0.282231591450947 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [273-393]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SAVKPTVSKV LPRTNNAAPA SRINACANST GTVKKNDVSN SVNNQQIEEM SNQVMDMRIN  60
   61 LEGLEKERDF YFSKLRDIEI LCQEADDAEA HPIIQKILDI LYATEDGFAP PDDAPPEDEE 120
  121 Y

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.522879
Match: 1txqB
Description: Crystal structure of the EB1 C-terminal domain complexed with the CAP-Gly domain of p150Glued
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle