YRC Public Data Repository - Protein Structure Prediction

Protein:	CG11043-PA
Organism:	Drosophila melanogaster
Length:	154 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG11043-PA.

Description	E-value	Query Range	Subject Range
COX4_SCHPO - Cytochrome c oxidase subunit 4, mitochondrial OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843)... cox4 - cytochrome c oxidase subunit IV	207.0	[0..4]	[152..2]
COX4_YEAST - Cytochrome c oxidase subunit 4, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288... gi\|190407127 - gi\|190407127\|gb\|EDV10394.1\| cytochrome c oxidase subunit IV [Saccharomyces cerevisiae RM11-1a] gi\|151943629 - gi\|151943629\|gb\|EDN61939.1\| cytochrome c oxidase subunit IV [Saccharomyces cerevisiae YJM789] COX4 - Subunit IV of cytochrome c oxidase, the terminal member of the mitochondrial inner membrane electron...	191.0	[0..13]	[152..5]
gi\|44984721, gi\|... - gi\|45198711\|ref\|NP_985740.1\| AFR193Wp [Ashbya gossypii ATCC 10895], gi\|44984721\|gb\|AAS53564.1\| AFR19... gi\|44984721 - gi\|44984721\|gb\|AAS53564.1\| AFR193Wp [Ashbya gossypii ATCC 10895]	188.0	[0..13]	[152..5]
gi\|74152883, gi\|... - gi\|74199859\|dbj\|BAE20757.1\| unnamed protein product [Mus musculus], gi\|74152883\|dbj\|BAE22451.1\| unna...	182.0	[0..30]	[150..3]
gi\|28416333 - gi\|28416333\|gb\|AAO42639.1\| RH49324p [Drosophila melanogaster]	182.0	[0..18]	[154..24]
COX5B_RAT - Cytochrome c oxidase subunit 5B, mitochondrial OS=Rattus norvegicus GN=Cox5b PE=1 SV=2	181.0	[0..30]	[150..3]
gi\|68466934, gi\|... - gi\|68466934\|ref\|XP_722382.1\| hypothetical protein CaO19.9046 [Candida albicans SC5314], gi\|68466651\|... orf19.9046, orf1... - COX4 CGDID:CAL0004689 Assembly 19, Contig19-10119 (52934, 53407) CDS, translated using codon table 1...	176.0	[0..9]	[152..7]
gi\|67536710, gi\|... - gi\|67536710\|ref\|XP_662129.1\| hypothetical protein AN4525.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	175.0	[0..15]	[153..11]

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Predicted Domain #1

Region A:
Residues: [1-154]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSYISRLLK AQSASKRLIS NLTQRDGKLS SLLRRLGLQW QGSAAAPQQR PISTTQVQKS  60
   61 ALIADDQLVT GIQKREMLLA KQGCEDPWGF SKVIRRGSGR ENDPTVVPSA FDARLVGCLC 120
  121 LDDRLPKWMW IEKDEGPKRC ECGHYFILKN VPPV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	39.0
Match:	1occF
Description:	Cytochrome c oxidase Subunit F
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
cytochrome-c oxidase activity	11.8078336041861	bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors	11.8078336041861	bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor	11.8078336041861	bayes_pls_golite062009
heme-copper terminal oxidase activity	11.4955994709345	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	5.35533851539468	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	5.20400060522221	bayes_pls_golite062009
electron carrier activity	4.79439258177657	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	4.61075334342911	bayes_pls_golite062009
oxidoreductase activity	4.60275002826443	bayes_pls_golite062009
cation transmembrane transporter activity	4.37169157675849	bayes_pls_golite062009
ion transmembrane transporter activity	4.17914534558054	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	3.78062052867494	bayes_pls_golite062009
substrate-specific transporter activity	3.5925267150231	bayes_pls_golite062009
binding	1.24038077894851	bayes_pls_golite062009
catalytic activity	0.176396048613815	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: