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View Structure Prediction Details

Protein: gi|114646066
Organism: Pan troglodytes
Length: 255 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|114646066.

Description E-value Query
Range
Subject
Range
MYF5 - myogenic factor 5
4.0E-63 [1..255] [1..255]
gi|109097930 - gi|109097930|ref|XP_001087187.1| PREDICTED: myogenic factor 5 [Macaca mulatta]
2.0E-62 [1..255] [1..255]
MYF5_MOUSE - Myogenic factor 5 OS=Mus musculus GN=Myf5 PE=1 SV=1
7.0E-61 [1..255] [1..255]
MYF5_BOVIN - Myogenic factor 5 OS=Bos taurus GN=MYF5 PE=2 SV=1
7.0E-58 [1..255] [1..255]
gi|45360427, gi|... - gi|89269838|emb|CAJ82544.1| myogenic factor 5 [Xenopus tropicalis], gi|45360427|ref|NP_988932.1| myo...
2.0E-57 [1..255] [1..255]
MYF5_XENLA - Myogenic factor 5 OS=Xenopus laevis GN=myf5 PE=2 SV=1
4.0E-57 [1..255] [1..255]
MYF5_NOTVI - Myogenic factor 5 OS=Notophthalmus viridescens GN=MYF-5 PE=2 SV=1
7.0E-56 [1..255] [1..256]
gi|109481950, gi... - gi|109481950|ref|XP_001080763.1| PREDICTED: similar to Myogenic factor 5 (Myf-5) [Rattus norvegicus]...
1.0E-55 [1..255] [73..327]
gi|73977483 - gi|73977483|ref|XP_852162.1| PREDICTED: similar to Myogenic factor 5 (Myf-5) isoform 2 [Canis famili...
2.0E-53 [1..255] [1..255]

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Predicted Domain #1
Region A:
Residues: [1-77]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDVMDGCQFS PSEYFYDGSC IPSPEGEFGD EFVPRVAAFG AHKAELQGSD EDEHVRAPTG  60
   61 HHQAGHCLMW ACKACKR

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 33.267606
Match: PF01586.7
Description: No description for PF01586.7 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [78-152]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSTTMDRRKA ATMRERRRLK KVNQAFETLK RCTTTNPNQR LPKVEILRNA IRYIESLQEL  60
   61 LREQVENYYS LPGQS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.30103
Match: 1mdyA
Description: Myod B/HLH domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.38658950816179 bayes_pls_golite062009
DNA binding 5.18654839258297 bayes_pls_golite062009
nucleic acid binding 5.05768805749761 bayes_pls_golite062009
transcription factor activity 4.78039531631248 bayes_pls_golite062009
transcription activator activity 3.87875547821718 bayes_pls_golite062009
binding 3.81829206350975 bayes_pls_golite062009
sequence-specific DNA binding 3.42035985454056 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.39500382187264 bayes_pls_golite062009
protein binding 2.64975291677725 bayes_pls_golite062009
transcription factor binding 2.61163564741984 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 2.42306484786159 bayes_pls_golite062009
promoter binding 1.56457725225443 bayes_pls_golite062009
transcription cofactor activity 1.52770895937238 bayes_pls_golite062009
transcription coactivator activity 1.39260472877067 bayes_pls_golite062009
transcription repressor activity 0.955588849035129 bayes_pls_golite062009
transcription corepressor activity 0.801830750183111 bayes_pls_golite062009
protein heterodimerization activity 0.53175615551166 bayes_pls_golite062009
structure-specific DNA binding 0.3655541712365 bayes_pls_golite062009
double-stranded DNA binding 0.29436315000437 bayes_pls_golite062009
protein dimerization activity 0.20674648626116 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [153-255]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CSEPTSPTSN CSDGMPECNS PVWSRKSSTF DSIYCPDVSN VYATDKNSLS SLDCLSNIVD  60
   61 RITSSEQPGL PLQDLASLSP VASTDSQPAT PGASSSRLIY HVL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle