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View Structure Prediction Details

Protein: gi|117371500
Organism: Plasmodium falciparum
Length: 227 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|117371500.

Description E-value Query
Range		 Subject
Range
gi|68065762 - gi|68065762|ref|XP_674865.1| translation initiation factor E4 [Plasmodium berghei strain ANKA]
gi|56493714 - gi|56493714|emb|CAH98210.1| translation initiation factor E4, putative [Plasmodium berghei]
 259.0 [0..1] [227..1]
gi|23480152 - gi|23480152|gb|EAA16793.1| putative initiation factor E4 [Plasmodium yoelii yoelii]
gi|82593968 - gi|82593968|ref|XP_725228.1| initiation factor E4 [Plasmodium yoelii yoelii str. 17XNL]
 259.0 [0..1] [227..1]
gi|50746789 - gi|50746789|ref|XP_420655.1| PREDICTED: similar to eIF-4E [Gallus gallus]
 229.0 [0..10] [220..60]
gi|94370433 - gi|94370433|ref|XP_930840.2| PREDICTED: similar to eIF-4E [Mus musculus]
 224.0 [0..9] [220..17]
gi|109629725 - gi|109629725|gb|ABG35117.1| eukaryotic translation initiation factor 4E [Pisum sativum]
 223.0 [0..7] [218..29]
IF4E_MOUSE - Eukaryotic translation initiation factor 4E OS=Mus musculus GN=Eif4e PE=1 SV=1
IF4E_RAT - Eukaryotic translation initiation factor 4E OS=Rattus norvegicus GN=Eif4e PE=1 SV=1
 223.0 [0..9] [220..17]
gi|67969074 - gi|67969074|dbj|BAE00892.1| unnamed protein product [Macaca fascicularis]
 221.0 [0..13] [220..44]
IF4E_RABIT - Eukaryotic translation initiation factor 4E OS=Oryctolagus cuniculus GN=EIF4E PE=1 SV=1
 220.0 [0..13] [220..21]

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Predicted Domain #1
Region A:
Residues: [1-227] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKYLTFNKNN RDAIDLSEKL EATKIDLSNP LLLQYNWVIW EQVSDNKIKQ SNNYKDYTRP  60
   61 LAKFNSVQKF WQLWNRLPQP SDLLAQRSMT RFSEDGIFRI VDALMIFRDN IQPMWEDPAN 120
  121 SGGGHFEYKI LPKDYPYSQI DEFWNNLVLA IIGCSLKHYD LITGIRLVDK LSTTRYGYIR 180
  181 IEIWYTTITD ESVKNYLRKD LEEHMCNRID GSTIFPPRVK SLSHIHR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 57.39794
Match: 1ipbA
Description: Translation initiation factor eIF4e
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
translation initiation factor activity 12.6022960879923 bayes_pls_golite062009
RNA cap binding 9.58762092856452 bayes_pls_golite062009
translation factor activity, nucleic acid binding 7.91586572659635 bayes_pls_golite062009
translation regulator activity 7.87578736455963 bayes_pls_golite062009
nucleic acid binding 3.46353214508261 bayes_pls_golite062009
binding 2.88787215275737 bayes_pls_golite062009
RNA binding 2.50528352006389 bayes_pls_golite062009
RNA 7-methylguanosine cap binding 0.544036568660606 bayes_pls_golite062009
protein binding 0.153677987194444 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle