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View Structure Prediction Details

Protein: gi|123998539, gi...
Organism: synthetic construct
Length: 700 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|123998539, gi....

Description E-value Query
Range
Subject
Range
gi|30585111, gi|... - gi|60653341|gb|AAX29365.1| v-myb myeloblastosis viral oncogene-like 2 [synthetic construct], gi|3058...
0.0 [1..700] [1..700]
gi|62898696 - gi|62898696|dbj|BAD97202.1| MYB-related protein B variant [Homo sapiens]
0.0 [1..700] [1..700]
gi|109092005 - gi|109092005|ref|XP_001084853.1| PREDICTED: MYB-related protein B [Macaca mulatta]
0.0 [1..700] [1..700]
gi|73992474 - gi|73992474|ref|XP_534424.2| PREDICTED: similar to Myb-related protein B (B-Myb) [Canis familiaris]
0.0 [11..700] [194..883]
gi|109469185, gi... - gi|109471257|ref|XP_001070125.1| PREDICTED: similar to Myb-related protein B (B-Myb) [Rattus norvegi...
0.0 [1..700] [1..705]
gi|55250785 - gb|AAH85989.1| Unknown (protein for MGC:97995) [Xenopus laevis]
MYBB_MOUSE - Myb-related protein B OS=Mus musculus GN=Mybl2 PE=1 SV=1
0.0 [1..700] [1..704]
gi|115495777, gi... - gi|115495777|ref|NP_001068916.1| v-myb myeloblastosis viral oncogene homolog (avian)-like 2 [Bos tau...
0.0 [1..700] [1..695]
MYBB_CHICK - Myb-related protein B OS=Gallus gallus GN=MYBL2 PE=1 SV=1
0.0 [1..700] [1..686]
gi|114682185 - gi|114682185|ref|XP_514658.2| PREDICTED: hypothetical protein [Pan troglodytes]
0.0 [1..625] [1..625]

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Predicted Domain #1
Region A:
Residues: [1-188]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRRTRCEDL DELHYQDTDS DVPEQRDSKC KVKWTHEEDE QLRALVRQFG QQDWKFLASH  60
   61 FPNRTDQQCQ YRWLRVLNPD LVKGPWTKEE DQKVIELVKK YGTKQWTLIA KHLKGRLGKQ 120
  121 CRERWHNHLN PEVKKSCWTE EEDRIICEAH KVLGNRWAEI AKMLPGRTDN AVKNHWNSTI 180
  181 KRKVDTGG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 49.154902
Match: 1h88C
Description: c-Myb, DNA-binding domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.13863038737912 bayes_pls_golite062009
DNA binding 4.66369707598026 bayes_pls_golite062009
nucleic acid binding 4.51452285155271 bayes_pls_golite062009
transcription factor activity 4.06706589695599 bayes_pls_golite062009
binding 3.02779747447702 bayes_pls_golite062009
sequence-specific DNA binding 2.41271657675151 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.26183812259792 bayes_pls_golite062009
transcription repressor activity 1.91962622287073 bayes_pls_golite062009
transcription activator activity 1.77700860354597 bayes_pls_golite062009
transcription factor binding 1.40653841901929 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.14886080629275 bayes_pls_golite062009
chromatin binding 1.04132983826241 bayes_pls_golite062009
transcription cofactor activity 0.84983974758882 bayes_pls_golite062009
protein binding 0.830419844171551 bayes_pls_golite062009
transcription corepressor activity 0.25931464844298 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.0585532752852558 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [189-272]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FLSESKDCKP PVYLLLELED KDGLQSAQPT EGQGSLLTNW PSVPPTIKEE ENSEEELAAA  60
   61 TTSKEQEPIG TDLDAVRTPE PLEE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [273-415]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FPKREDQEGS PPETSLPYKW VVEAANLLIP AVGSSLSEAL DLIESDPDAW CDLSKFDLPE  60
   61 EPSAEDSINN SLVQLQASHQ QQVLPPRQPS ALVPSVTEYR LDGHTISDLS RSSRGELIPI 120
  121 SPSTEVGGSG IGTPPSVLKR QRK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [416-700]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RRVALSPVTE NSTSLSFLDS CNSLTPKSTP VKTLPFSPSQ FLNFWNKQDT LELESPSLTS  60
   61 TPVCSQKVVV TTPLHRDKTP LHQKHAAFVT PDQKYSMDNT PHTPTPFKNA LEKYGPLKPL 120
  121 PQTPHLEEDL KEVLRSEAGI ELIIEDDIRP EKQKRKPGLR RSPIKKVRKS LALDIVDEDV 180
  181 KLMMSTLPKS LSLPTTAPSN SSSLTLSGIK EDNSLLNQGF LQAKPEKAAV AQKPRSHFTT 240
  241 PAPMSSAWKT VACGGTRDQL FMQEKARQLL GRLKPSHTSR TLILS

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 104.39794
Match: PF09316.1
Description: No description for PF09316.1 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle