YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|121587480, gi...
Organism:	Vibrio cholerae 2740-80
Length:	230 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|121587480, gi....

Description	E-value	Query Range	Subject Range
gi\|75702476, gi\|... - gi\|75908751\|ref\|YP_323047.1\| GTP cyclohydrolase I [Anabaena variabilis ATCC 29413], gi\|75702476\|gb\|A...	318.0	[0..2]	[230..5]
gi\|25290301 - pir\|\|AG2466 GTP cyclohydrolase I [imported] - Nostoc sp. (strain PCC 7120) GCH11_NOSS1 - GTP cyclohydrolase 1 1 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=folE1 PE=3 SV=1	315.0	[0..2]	[230..5]
gi\|46118361, gi\|... - gi\|67925134\|ref\|ZP_00518508.1\| GTP cyclohydrolase I [Crocosphaera watsonii WH 8501], gi\|67853028\|gb\|...	313.0	[0..26]	[230..34]
gi\|254849776, gi... - gi\|75831523\|ref\|ZP_00760786.1\| COG0302: GTP cyclohydrolase I [Vibrio cholerae MO10], gi\|254849776\|re... GCH1_VIBCH - GTP cyclohydrolase 1 OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) GN=fol... gi\|229356568, gi... - gi\|229506217\|ref\|ZP_04395726.1\| GTP cyclohydrolase I type 1 [Vibrio cholerae BX 330286], gi\|22935656... gi\|229509924, gi... - gi\|229509924\|ref\|ZP_04399404.1\| GTP cyclohydrolase I type 1 [Vibrio cholerae B33], gi\|229352369\|gb\|E... gi\|229349605, gi... - gi\|229513195\|ref\|ZP_04402660.1\| GTP cyclohydrolase I type 1 [Vibrio cholerae TMA 21], gi\|229349605\|g... gi\|229346396, gi... - gi\|229516515\|ref\|ZP_04405962.1\| GTP cyclohydrolase I type 1 [Vibrio cholerae RC9], gi\|229346396\|gb\|E... gi\|229523112, gi... - gi\|229523112\|ref\|ZP_04412524.1\| GTP cyclohydrolase I type 1 [Vibrio cholerae TM 11079-80], gi\|229339... gi\|229525973, gi... - gi\|229525973\|ref\|ZP_04415377.1\| GTP cyclohydrolase I type 1 [Vibrio cholerae bv. albensis VL426], gi... gi\|229528553, gi... - gi\|229528553\|ref\|ZP_04417944.1\| GTP cyclohydrolase I type 1 [Vibrio cholerae 12129(1)], gi\|229334915... gi\|229605757, gi... - gi\|229605757\|ref\|YP_002876461.1\| GTP cyclohydrolase I type 1 [Vibrio cholerae MJ-1236], gi\|229372243... gi\|124120549, gi... - gi\|153219989\|ref\|ZP_01951558.1\| GTP cyclohydrolase I [Vibrio cholerae MAK 757], gi\|124120549\|gb\|EAY3... GCH1_VIBCH - GTP cyclohydrolase 1 OS=Vibrio cholerae GN=folE PE=3 SV=2 gi\|75825439 - gi\|75825439\|ref\|ZP_00754875.1\| COG0302: GTP cyclohydrolase I [Vibrio cholerae O395] gi\|75822045, gi\|... - gi\|75822045\|ref\|ZP_00751756.1\| COG0302: GTP cyclohydrolase I [Vibrio cholerae RC385], gi\|116215375\|r... gi\|75820105, gi\|... - gi\|75820105\|ref\|ZP_00750161.1\| COG0302: GTP cyclohydrolase I [Vibrio cholerae V51], gi\|116220666\|ref... gi\|75817221 - gi\|75817221\|ref\|ZP_00747674.1\| COG0302: GTP cyclohydrolase I [Vibrio cholerae V52]	313.0	[0..14]	[230..1]
GCH1_SYNEL - GTP cyclohydrolase 1 OS=Synechococcus elongatus GN=folE PE=3 SV=1 GCH1_THEEB - GTP cyclohydrolase 1 OS=Thermosynechococcus elongatus (strain BP-1) GN=folE PE=3 SV=1	313.0	[0..21]	[230..18]
GCH1_NOSP7 - GTP cyclohydrolase 1 OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102) GN=folE PE=3 SV=1	312.0	[0..2]	[230..5]
GCH1_SYNE7 - GTP cyclohydrolase 1 OS=Synechococcus elongatus (strain PCC 7942) GN=folE PE=3 SV=2 GCH1_SYNP6 - GTP cyclohydrolase 1 OS=Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) GN=folE PE=3 ...	311.0	[0..42]	[230..19]
gi\|45513086, gi\|... - ref\|ZP_00164652.1\| COG0302: GTP cyclohydrolase I [Synechococcus elongatus PCC 7942], gi\|1399847\|gb\|...	311.0	[0..42]	[230..21]
GCH1_SYNY3 - GTP cyclohydrolase 1 OS=Synechocystis sp. (strain ATCC 27184 / PCC 6803 / N-1) GN=folE PE=3 SV=1 GCH1_SYNY3 - GTP cyclohydrolase 1 OS=Synechocystis sp. (strain PCC 6803 / Kazusa) GN=folE PE=3 SV=1 gi\|7435993 - pir\|\|S76560 GTP cyclohydrolase I (EC 3.5.4.16) - Synechocystis sp. (strain PCC 6803)	310.0	[0..11]	[230..10]

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Predicted Domain #1

Region A:
Residues: [1-230]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAIRKGYLR GRGMSGLSES AKLVKDALER RGLETPMQPN LATPAEKKEK IEQHMREILN  60
   61 LLGLDLTDDS LEETPQRIAK MYVDEIFSGL DYANFPKITV IENKMKVSEM VKVKDITLTS 120
  121 TCEHHLVTID GTAAVAYIPR GKIIGLSKIN RIVRFFAQRP QVQERMTQQI LVALQTLLES 180
  181 DDVAVTIDAT HYCVKSRGVM DATSVTTTTA LGGIFKSNPA TRAEFLHGLR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	73.221849
Match:	1fbxA
Description:	GTP cyclohydrolase I
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
GTP cyclohydrolase I activity	4.1430878480831	bayes_pls_golite062009
cyclohydrolase activity	3.66553359909123	bayes_pls_golite062009
GTP cyclohydrolase activity	3.44912994722205	bayes_pls_golite062009
catalytic activity	2.20788162511962	bayes_pls_golite062009
dihydroneopterin aldolase activity	1.96466418682643	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	1.73101699306211	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	0.974891318710762	bayes_pls_golite062009
binding	0.392476729829125	bayes_pls_golite062009
carbon-carbon lyase activity	0.25616855487144	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: