YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|114681558
Organism:	Pan troglodytes
Length:	432 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|114681558.

Description	E-value	Query Range	Subject Range
gi\|138519669, gi... - gi\|89269565\|emb\|CAJ82626.1\| S-adenosylhomocysteine hydrolase [Xenopus tropicalis], gi\|138519669\|gb\|A...	0.0	[1..432]	[1..433]
SAHHA_XENLA - Adenosylhomocysteinase A OS=Xenopus laevis GN=ahcy-a PE=2 SV=1	0.0	[1..432]	[1..433]
gi\|904132, gi\|77... - gi\|904132\|gb\|AAA70378.1\| copper binding protein, ref\|NP_057870.1\| S-adenosylhomocysteine hydrolase [...	0.0	[1..432]	[1..432]
gi\|40363541, gi\|... - gi\|40363541\|ref\|NP_954688.1\| S-adenosylhomocysteine hydrolase [Danio rerio], gi\|37681725\|gb\|AAQ97740...	0.0	[1..432]	[1..433]
gi\|54297948, gi\|... - gi\|54297948\|ref\|YP_124317.1\| S-adenosyl-L-homocysteine hydrolase [Legionella pneumophila str. Paris]...	0.0	[5..432]	[15..441]

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Predicted Domain #1

Region A:
Residues: [1-432]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDKLPYKVA DIGLAAWGRK ALDIAENEMP GLMRMRERYS ASKPLKGARI AGCLHMTVET  60
   61 AVLIETLVTL GAEVQWSSCN IFSTQDHAAA AIAKAGIPVY AWKGETDEEY LWCIEQTLYF 120
  121 KDGPLNMILD DGGDLTNLIH TKYPQLLPGI RGISEETTTG VHNLYKMMAN GILKVPAINV 180
  181 NDSVTKSKFD NLYGCRESLI DGIKRATDVM IAGKVAVVAG YGDVGKGCAQ ALRGFGARVI 240
  241 ITEIDPINAL QAAMEGYEVT TMDEACQEGN IFVTTTGCID IILGRHFEQM KDDAIVCNIG 300
  301 HFDVEIDVKW LNENAVEKVN IKPQVDRYRL KNGRRIILLA EGRLVNLGCA MGHPSFVMSN 360
  361 SFTNQVMAQI ELWTHPDKYP VGVHFLPKKL DEAVAEAHLG KLNVKLTKLT EKQAQYLGMS 420
  421 CDGPFKPDHY RY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	159.0
Match:	1li4A
Description:	S-adenosylhomocystein hydrolase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
adenosylhomocysteinase activity	4.75102111339352	bayes_pls_golite062009
trialkylsulfonium hydrolase activity	4.75102111339352	bayes_pls_golite062009
catalytic activity	1.79741889688267	bayes_pls_golite062009
oxidoreductase activity	0.9367410227151	bayes_pls_golite062009
binding	0.784517759335365	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	0.418775403210681	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.32207755075663	bayes_pls_golite062009
DNA binding	0.158019531459925	bayes_pls_golite062009
nucleic acid binding	0.0191997392158629	bayes_pls_golite062009
transcription regulator activity	0.012678711735872	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: