YRC Public Data Repository - Protein Structure Prediction

Protein:	STXB1_RAT
Organism:	Rattus norvegicus
Length:	594 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for STXB1_RAT.

Description	E-value	Query Range	Subject Range
gi\|17225417 - gi\|17225417\|gb\|AAL37391.1\|AF326545_1 syntaxin binding protein 1 [Mus musculus]	0.0	[1..594]	[1..594]
gi\|435430, gi\|73... - gi\|738775\|prf\|\|2001428B syntaxin-binding synaptic protein, gi\|435430\|gb\|AAB41112.1\| Munc18-1 [Bos ta...	0.0	[1..594]	[1..594]
STXB1_CHICK - Syntaxin-binding protein 1 OS=Gallus gallus GN=STXBP1 PE=2 SV=1	0.0	[1..594]	[1..594]
gi\|631898 - gi\|631898\|pir\|\|S39345 unc-18 protein homolog, 67K - rat	0.0	[1..594]	[1..594]
gi\|51261450, gi\|... - gi\|51261450\|gb\|AAH80023.1\| LOC100101272 protein [Xenopus laevis], gi\|153792420\|ref\|NP_001093335.1\| h...	0.0	[1..594]	[1..595]
ENSMMUG000000164... - null, null ENSCJAT00000038932 - null tr\|F6R0H3\|F6R0H3... - Isoform of P61763, Syntaxin-binding protein 1 OS=Bos taurus GN=STXBP1 PE=4 SV=1 gi\|119608087, gi... - gi\|57208971\|emb\|CAI41180.1\| syntaxin binding protein 1 [Homo sapiens], gi\|4507297\|ref\|NP_003156.1\| s... gi\|165972307, gi... - gi\|21594764\|gb\|AAH31728.1\| Stxbp1 protein [Mus musculus], gi\|165972307\|ref\|NP_001107041.1\| syntaxin ... gi\|149038988, gi... - gi\|755493\|gb\|AAA96350.1\| rbSec1B, gi\|149038988\|gb\|EDL93208.1\| syntaxin binding protein 1, isoform CR...	0.0	[1..584]	[1..584]
gi\|118405042, gi... - gi\|118405042\|ref\|NP_001072521.1\| syntaxin binding protein 1 [Xenopus (Silurana) tropicalis], gi\|1152...	0.0	[1..584]	[1..585]

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Predicted Domain #1

Region A:
Residues: [1-594]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPIGLKAVV GEKIMHDVIK KVKKKGEWKV LVVDQLSMRM LSSCCKMTDI MTEGITIVED  60
   61 INKRREPLPS LEAVYLITPS EKSVHSLISD FKDPPTAKYR AAHVFFTDSC PDALFNELVK 120
  121 SRAAKVIKTL TEINIAFLPY ESQVYSLDSA DSFQSFYSPH KAQMKNPILE RLAEQIATLC 180
  181 ATLKEYPAVR YRGEYKDNAL LAQLIQDKLD AYKADDPTMG EGPDKARSQL LILDRGFDPS 240
  241 SPVLHELTFQ AMSYDLLPIE NDVYKYETSG IGEARVKEVL LDEDDDLWIA LRHKHIAEVS 300
  301 QEVTRSLKDF SSSKRMNTGE KTTMRDLSQM LKKMPQYQKE LSKYSTHLHL AEDCMKHYQG 360
  361 TVDKLCRVEQ DLAMGTDAEG EKIKDPMRAI VPILLDANVS TYDKIRIILL YIFLKNGITE 420
  421 ENLNKLIQHA QIPPEDSEII TNMAHLGVPI VTDSTLRRRS KPERKERISE QTYQLSRWTP 480
  481 IIKDIMEDTI EDKLDTKHYP YISTRSSASF STTAVSARYG HWHKNKAPGE YRSGPRLIIF 540
  541 ILGGVSLNEM RCAYEVTQAN GKWEVLIGST HILTPQKLLD TLKKLNKTDE EISS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1dn1A
Description:	Neuronal Sec1, NSec1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
SNARE binding	4.56428593085019	bayes_pls_golite062009
syntaxin binding	3.46044132736061	bayes_pls_golite062009
binding	2.7837022903231	bayes_pls_golite062009
protein binding	1.7224010512877	bayes_pls_golite062009
syntaxin-1 binding	0.269372794919901	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: