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View Structure Prediction Details

Protein: HXA7_RAT
Organism: Rattus norvegicus
Length: 105 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HXA7_RAT.

Description E-value Query
Range
Subject
Range
HXA7_MOUSE - Homeobox protein Hox-A7 OS=Mus musculus GN=Hoxa7 PE=2 SV=2
121.0 [0..2] [90..126]
gi|158711670, gi... - gi|62647267|ref|XP_575478.1| PREDICTED: similar to Hoxa7 [Rattus norvegicus], gi|158711670|ref|NP_00...
120.0 [0..2] [90..126]
gi|34398398 - gi|34398398|gb|AAQ67266.1| antennapedia [Drosophila virilis]
112.0 [0..4] [85..298]
gi|9621907 - gi|9621907|gb|AAF89581.1|AF165886_1 paired-box transcription factor [Branchiostoma floridae]
112.0 [0..1] [102..185]
UNCX - UNC homeobox
112.0 [0..2] [91..102]
gi|4322038 - gi|4322038|gb|AAD15929.1| homeobox protein [Petromyzon marinus]
111.0 [0..2] [77..224]
gi|15425738, gi|... - gi|15425738|dbj|BAB64346.1| homeotic protein [Daphnia magna], gi|109944931|dbj|BAE96993.1| Antennape...
111.0 [0..4] [67..545]

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Predicted Domain #1
Region A:
Residues: [1-105]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGPDGKRGRQ TYTRYQTLEL EKEFHFNRYL TRRRAVEIAH ALCLTERQIK IWFQNRRMKW  60
   61 KKEHKDESQA PTAVPEDAVP SVSTAADKAD EEEEEEEEEE EEEEE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.522879
Match: 1homA
Description: DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF THE ANTENNAPEDIA HOMEODOMAIN FROM DROSOPHILA IN SOLUTION BY 1H NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 2.82910876106939 bayes_pls_golite062009
DNA binding 2.71139715874068 bayes_pls_golite062009
binding 2.59102816487173 bayes_pls_golite062009
nucleic acid binding 2.4041998404334 bayes_pls_golite062009
transcription factor activity 2.30605638403993 bayes_pls_golite062009
sequence-specific DNA binding 1.81835017168096 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.46122830109379 bayes_pls_golite062009
protein binding 0.853351196918381 bayes_pls_golite062009
transcription activator activity 0.81440394306575 bayes_pls_golite062009
transcription repressor activity 0.77814500281111 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.57338514991304 bayes_pls_golite062009
transcription factor binding 0.22865859991459 bayes_pls_golite062009
chromatin binding 0.203837749053719 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle