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View Structure Prediction Details

Protein: PSA7_MOUSE
Organism: Mus musculus
Length: 248 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PSA7_MOUSE.

Description E-value Query
Range
Subject
Range
gi|116283481 - gi|116283481|gb|AAH14999.1| PSMA7 protein [Homo sapiens]
266.0 [0..1] [238..1]
gi|74145096 - gi|74145096|dbj|BAE27417.1| unnamed protein product [Mus musculus]
265.0 [0..1] [230..1]
gi|34860906, gi|... - gi|62646494|ref|XP_579184.1| PREDICTED: proteasome (prosome, macropain) subunit, alpha type 7 [Rattu...
264.0 [0..1] [230..1]
PSA7_BOVIN - Proteasome subunit alpha type-7 OS=Bos taurus GN=PSMA7 PE=1 SV=1
263.0 [0..1] [230..1]
gi|61373076, gi|... - gi|61373078|gb|AAX43973.1| proteasome subunit alpha type 7 [synthetic construct], gi|61373076|gb|AAX...
260.0 [0..1] [230..1]
PSA7B_XENLA - Proteasome subunit alpha type-7-B OS=Xenopus laevis GN=psma7-b PE=2 SV=1
260.0 [0..1] [230..1]
PSA7A_XENLA - Proteasome subunit alpha type-7-A OS=Xenopus laevis GN=psma7-a PE=2 SV=1
gi|89268296, gi|... - gi|89268296|emb|CAJ83094.1| proteasome (prosome macropain) subunit alpha type7 [Xenopus tropicalis],...
260.0 [0..1] [230..1]

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Predicted Domain #1
Region A:
Residues: [1-248]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYDRAITVF SPDGHLFQVE YAQEAVKKGS TAVGVRGKDI VVLGVEKKSV AKLQDERTVR  60
   61 KICALDDNVC MAFAGLTADA RIVINRARVE CQSHRLTVED PVTVEYITRY IASLKQRYTQ 120
  121 SNGRRPFGIS ALIVGFDFDG TPRLYQTDPS GTYHAWKANA IGRGAKSVRE FLEKNYTDDA 180
  181 IETDDLTIKL VIKALLEVVQ SGGKNIELAV MRRDQPLKIL NPEEIEKYVA EIEKEKEENE 240
  241 KKKQKKAS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 69.39794
Match: 1iruD
Description: Proteasome alpha subunit (non-catalytic)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
endopeptidase activity 6.91642761177919 bayes_pls_golite062009
peptidase activity 6.84511694091156 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 6.5973571808298 bayes_pls_golite062009
hydrolase activity 4.47652590304822 bayes_pls_golite062009
threonine-type endopeptidase activity 2.98214579292788 bayes_pls_golite062009
threonine-type peptidase activity 2.98214579292788 bayes_pls_golite062009
binding 1.75265921676176 bayes_pls_golite062009
nucleic acid binding 1.39216781236247 bayes_pls_golite062009
catalytic activity 1.19663085909195 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle