YRC Public Data Repository - Protein Structure Prediction

Protein:	MCTS1_MOUSE
Organism:	Mus musculus
Length:	181 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MCTS1_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|50746002 - gi\|50746002\|ref\|XP_420334.1\| PREDICTED: similar to malignant T cell amplified sequence 1; MCT-1 prot...	233.0	[0..1]	[181..139]
gi\|73949188 - gi\|73949188\|ref\|XP_544278.2\| PREDICTED: similar to malignant T cell amplified sequence 1 [Canis fami...	231.0	[0..1]	[181..158]
ENSCJAT00000004957 - null MCTS1_BOVIN - Malignant T-cell-amplified sequence 1 OS=Bos taurus GN=MCTS1 PE=2 SV=1 gi\|74008257 - gi\|74008257\|ref\|XP_864674.1\| PREDICTED: similar to malignant T cell amplified sequence 1 isoform 3 [... gi\|114690028 - gi\|114690028\|ref\|XP_001137540.1\| PREDICTED: malignant T cell amplified sequence 1 isoform 3 [Pan tro... MCTS1 - malignant T cell amplified sequence 1	223.0	[0..1]	[181..1]
MCS1A_XENLA - Malignant T-cell-amplified sequence 1-A OS=Xenopus laevis GN=mcts1-a PE=2 SV=1	223.0	[0..1]	[181..1]
gi\|55742194 - ref\|NP_001006880.1\| malignant T cell amplified sequence 1 [Xenopus tropicalis] MCTS1_XENTR - Malignant T-cell-amplified sequence 1 OS=Xenopus tropicalis GN=mcts1 PE=2 SV=1	222.0	[0..1]	[181..1]
gi\|154152173, gi... - gi\|76665894\|ref\|XP_593366.2\| PREDICTED: hypothetical protein isoform 1 [Bos taurus], gi\|154152173\|re...	222.0	[0..1]	[181..1]
gi\|109132131 - gi\|109132131\|ref\|XP_001086431.1\| PREDICTED: similar to malignant T cell amplified sequence 1 isoform...	219.0	[0..1]	[181..1]
gi\|108876300, gi... - gi\|157116754\|ref\|XP_001658619.1\| mct-1 protein [Aedes aegypti], gi\|108876300\|gb\|EAT40525.1\| mct-1 pr...	218.0	[0..1]	[181..1]

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Predicted Domain #1

Region A:
Residues: [1-181]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFKKFDEKEN VSNCIQLKTS VIKGIKNQLL EQFPGIEPWL NQIMPKKDPV KIVRCHEHIE  60
   61 ILTVNGELLF FRQREGPFYP TLRLLHKYPF ILPHQQVDKG AIKFVLSGAN IMCPGLTSPG 120
  121 AKLYPAAVDT IVAIMAEGKQ HALCVGVMKM SAEDIEKVNK GIGIENIHYL NDGLWHMKTY 180
  181 K

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	34.522879
Match:	2apoA
Description:	Crystal Structure of the Methanococcus jannaschii Cbf5 Nop10 Complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein binding	1.42723828072353	bayes_pls_golite062009
binding	1.32705610464746	bayes_pls_golite062009
nucleic acid binding	0.494497910595989	bayes_pls_golite062009
transcription regulator activity	0.280679512188409	bayes_pls_golite062009
DNA binding	0.161277478498683	bayes_pls_golite062009
catalytic activity	0.147263815852997	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: