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View Structure Prediction Details

Protein: CSRP3_MOUSE
Organism: Mus musculus
Length: 194 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CSRP3_MOUSE.

Description E-value Query
Range
Subject
Range
gi|114647257 - gi|114647257|ref|XP_001159746.1| PREDICTED: paxillin isoform 2 [Pan troglodytes]
177.0 [0..9] [193..321]
gi|73995303 - gi|73995303|ref|XP_543425.2| PREDICTED: similar to Paxillin [Canis familiaris]
176.0 [0..9] [193..430]
gi|47214002 - gi|47214002|emb|CAG01877.1| unnamed protein product [Tetraodon nigroviridis]
173.0 [0..9] [193..354]
gi|76639291 - gi|76639291|ref|XP_595626.2| PREDICTED: similar to Paxillin [Bos taurus]
173.0 [0..9] [193..399]
gi|157169820 - gi|157169820|gb|AAI52795.1| Paxillin [synthetic construct]
gi|114326502 - gi|114326502|ref|NP_598676.2| paxillin isoform beta [Mus musculus]
170.0 [0..9] [193..357]
PAXI_RAT - Paxillin OS=Rattus norvegicus GN=Pxn PE=1 SV=1
170.0 [0..9] [193..352]

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Predicted Domain #1
Region A:
Residues: [1-194]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPNWGGGAKC GACEKTVYHA EEIQCNGRSF HKTCFHCMAC RKALDSTTVA AHESEIYCKV  60
   61 CYGRRYGPKG IGFGQGAGCL STDTGEHLGL QFQQSPKPAR AATTSNPSKF SAKFGESEKC 120
  121 PRCGKSVYAA EKVMGGGKPW HKTCFRCAIC GKSLESTNVT DKDGELYCKV CYAKNFGPTG 180
  181 IGFGGLTQQV EKKE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.39794
Match: 1b8tA
Description: Cysteine-rich (intestinal) protein, CRP, CRIP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
actin binding 3.16886380675327 bayes_pls_golite062009
binding 2.96409924710655 bayes_pls_golite062009
protein binding 2.44501340584871 bayes_pls_golite062009
cytoskeletal protein binding 2.31497455728997 bayes_pls_golite062009
transcription regulator activity 2.22839475692516 bayes_pls_golite062009
DNA binding 1.96428761552366 bayes_pls_golite062009
actin filament binding 1.88919389919607 bayes_pls_golite062009
nucleic acid binding 1.73351698570585 bayes_pls_golite062009
transcription activator activity 1.60639114794515 bayes_pls_golite062009
sequence-specific DNA binding 1.59705128803795 bayes_pls_golite062009
transcription factor activity 1.41077905480556 bayes_pls_golite062009
receptor activity 1.05205471090697 bayes_pls_golite062009
ligand-dependent nuclear receptor activity 0.55799224325565 bayes_pls_golite062009
transcription factor binding 0.43597775400036 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.30102391671156 bayes_pls_golite062009
myosin binding 0.208886721497353 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.10722537662857 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle