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View Structure Prediction Details

Protein: CD3D_MOUSE
Organism: Mus musculus
Length: 173 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CD3D_MOUSE.

Description E-value Query
Range
Subject
Range
gi|109108856 - gi|109108856|ref|XP_001097302.1| PREDICTED: CD3d molecule, delta (CD3-TCR complex) [Macaca mulatta]
148.0 [0..1] [171..1]
CD3D_MACFA - T-cell surface glycoprotein CD3 delta chain OS=Macaca fascicularis GN=CD3D PE=2 SV=1
147.0 [0..1] [171..1]
gi|57085933 - gi|57085933|ref|XP_536556.1| PREDICTED: similar to T-cell surface glycoprotein CD3 delta chain precu...
147.0 [0..1] [171..1]
CD3D - CD3d molecule, delta (CD3-TCR complex)
145.0 [0..1] [171..1]
gi|114640611 - gi|114640611|ref|XP_508789.2| PREDICTED: hypothetical protein [Pan troglodytes]
144.0 [0..1] [171..1]
gi|61098090, gi|... - gi|61098090|ref|NP_038515.2| CD3 antigen, delta polypeptide [Mus musculus], gi|38571756|gb|AAH62807....
143.0 [0..1] [173..1]
CD3D_RAT - T-cell surface glycoprotein CD3 delta chain OS=Rattus norvegicus GN=Cd3d PE=2 SV=1
141.0 [0..1] [173..1]

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Predicted Domain #1
Region A:
Residues: [1-98]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEHSGILASL ILIAVLPQGS PFKIQVTEYE DKVFVTCNTS VMHLDGTVEG WFAKNKTLNL  60
   61 GKGVLDPRGI YLCNGTEQLA KVVSSVQVHY RMCQNCVE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.045757
Match: 1xiwB
Description: Crystal structure of human CD3-e/d dimer in complex with a UCHT1 single-chain antibody fragment
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
receptor activity 4.00123250685257 bayes_pls_golite062009
transmembrane receptor activity 3.81769911097805 bayes_pls_golite062009
antigen binding 3.16266926144655 bayes_pls_golite062009
molecular transducer activity 3.10913345555941 bayes_pls_golite062009
signal transducer activity 3.10913345555941 bayes_pls_golite062009
binding 2.53652619212064 bayes_pls_golite062009
T cell receptor binding 2.12089279430732 bayes_pls_golite062009
peptide antigen binding 1.66960790017756 bayes_pls_golite062009
protein binding 1.17809977833322 bayes_pls_golite062009
G-protein coupled receptor activity 1.02428106476324 bayes_pls_golite062009
receptor binding 0.909733688848793 bayes_pls_golite062009
immunoglobulin binding 0.84834833214265 bayes_pls_golite062009
protein complex binding 0.83543827718565 bayes_pls_golite062009
peptide binding 0.729048089532569 bayes_pls_golite062009
coreceptor activity 0.661209696849389 bayes_pls_golite062009
growth factor binding 0.53454839799174 bayes_pls_golite062009
transmembrane receptor protein kinase activity 0.447829399094714 bayes_pls_golite062009
transmembrane receptor protein tyrosine kinase activity 0.28309679787333 bayes_pls_golite062009
olfactory receptor activity 0.20101044847022 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [99-173]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDSGTMAGVI FIDLIATLLL ALGVYCFAGH ETGRPSGAAE VQALLKNEQL YQPLRDREDT  60
   61 QYSRLGGNWP RNKKS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.69897
Match: 2dm3A
Description: No description for 2dm3A was found.

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