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View Structure Prediction Details

Protein: gi|12850634, gi|...
Organism: Mus musculus
Length: 291 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|12850634, gi|....

Description E-value Query
Range
Subject
Range
IMP4_RAT - U3 small nucleolar ribonucleoprotein protein IMP4 OS=Rattus norvegicus GN=Imp4 PE=2 SV=1
IMP4_MOUSE - U3 small nucleolar ribonucleoprotein protein IMP4 OS=Mus musculus GN=Imp4 PE=2 SV=1
345.0 [0..12] [291..12]
gi|22902285 - gi|22902285|gb|AAH37602.1| Imp4 protein [Mus musculus]
345.0 [0..12] [291..17]
gi|109104608 - gi|109104608|ref|XP_001093227.1| PREDICTED: similar to IMP4, U3 small nucleolar ribonucleoprotein, h...
343.0 [0..12] [291..12]
gi|55729975 - gi|55729975|emb|CAH91713.1| hypothetical protein [Pongo abelii]
gi|55729975|emb|... - hypothetical protein [Pongo pygmaeus]
343.0 [0..12] [291..11]
IMP4 - IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
gi|124000169, gi... - gi|157929232|gb|ABW03901.1| IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast) [synthetic c...
341.0 [0..12] [291..12]
gi|73993566 - gi|73993566|ref|XP_534545.2| PREDICTED: similar to IMP4, U3 small nucleolar ribonucleoprotein, homol...
340.0 [0..17] [291..65]
gi|66514411 - gi|66514411|ref|XP_395323.2| PREDICTED: similar to IMP4, U3 small nucleolar ribonucleoprotein, homol...
339.0 [0..1] [291..1]
IMP4_BOVIN - U3 small nucleolar ribonucleoprotein protein IMP4 OS=Bos taurus GN=IMP4 PE=2 SV=1
338.0 [0..12] [291..12]

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Predicted Domain #1
Region A:
Residues: [1-81]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRREARLRR EYLYRKAREE AHGSVQEKKE RVKRALEENQ LIPTELRREA LALQGSLEFD  60
   61 DAGGEGVTSH VDDEYRWAGV E

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [82-173]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPKVMITTSR DPSSRLKMFA KELKLVFPGA QRMNRGRHEV GALVRACKAN GVTDLLVVHE  60
   61 HRGTPVGLIV SHLPFGPTAY FTLCNVVMRH DI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.221849
Match: 2cxhA
Description: Crystal structure of probable ribosomal biogenesis protein from Aeropyrum pernix K1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
aminoacyl-tRNA ligase activity 3.58650371779212 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 3.58624422951947 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 3.58624422951947 bayes_pls_golite062009
ligase activity 2.71574082295198 bayes_pls_golite062009
proline-tRNA ligase activity 2.35871952544841 bayes_pls_golite062009
binding 1.73857064375258 bayes_pls_golite062009
catalytic activity 0.902495165806215 bayes_pls_golite062009
protein binding 0.358563180490135 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [174-291]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDLGTMSEAK PHLITHGFSS RLGKRVSDIL RYLFPVPKDD SHRVITFANQ DDYISFRHHV  60
   61 YKKTDHRNVE LTEVGPRFEL KLYMIRLGTL EQEATADVEW RWHPYTNTAR KRVFLSAE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.74
Match: 2cxhA
Description: Crystal structure of probable ribosomal biogenesis protein from Aeropyrum pernix K1
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle