YRC Public Data Repository - Protein Structure Prediction

Protein:	OVCA2_MOUSE
Organism:	Mus musculus
Length:	225 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for OVCA2_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|149053384, gi... - gi\|62656536\|ref\|XP_573140.1\| PREDICTED: similar to candidate tumor suppressor OVCA2 [Rattus norvegic...	184.0	[0..1]	[225..1]
gi\|30248854, gi\|... - gi\|30248854\|ref\|NP_840924.1\| phospholipase/carboxylesterase [Nitrosomonas europaea ATCC 19718], gi\|3...	171.0	[0..3]	[225..17]
gi\|88789693, gi\|... - gi\|88813060\|ref\|ZP_01128302.1\| Phospholipase/Carboxylesterase [Nitrococcus mobilis Nb-231], gi\|88789...	170.0	[0..3]	[224..23]
gi\|109086409 - gi\|109086409\|ref\|XP_001083287.1\| PREDICTED: lysophospholipase I isoform 2 [Macaca mulatta]	169.0	[0..2]	[224..17]
gi\|93006457, gi\|... - gi\|93006457\|ref\|YP_580894.1\| carboxylesterase [Psychrobacter cryohalolentis K5], gi\|92394135\|gb\|ABE7...	169.0	[0..9]	[224..23]
LYPA1_PONPY - Acyl-protein thioesterase 1 - Pongo pygmaeus (Orangutan) LYPA1_PONAB - Acyl-protein thioesterase 1 OS=Pongo abelii GN=LYPLA1 PE=2 SV=1	168.0	[0..2]	[224..17]
gi\|114620143 - gi\|114620143\|ref\|XP_519760.2\| PREDICTED: hypothetical protein isoform 4 [Pan troglodytes]	167.0	[0..2]	[224..17]
gi\|39795561, gi\|... - gi\|45361419\|ref\|NP_989287.1\| hypothetical protein LOC394905 [Xenopus (Silurana) tropicalis], gi\|3979...	167.0	[0..4]	[224..22]
gi\|119936523, gi... - gi\|122692349\|ref\|NP_001073831.1\| lysophospholipase II [Bos taurus], gi\|119936523\|gb\|ABM06143.1\| lyso...	167.0	[0..2]	[224..20]
gi\|161762492, gi... - gi\|95927767\|ref\|ZP_01310520.1\| hypothetical protein CburR_01000345 [Coxiella burnetii RSA 331], gi\|1...	167.0	[0..9]	[220..20]

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Predicted Domain #1

Region A:
Residues: [1-225]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAARQTLRVL CLAGFRQSER GFREKTGALR KTLRGRAELV CLSGPHPVPE AAAPEGSCPD  60
   61 SGPCSPEEQP RGWWFSEEEA DVFSALEEST VCRGLQEALE TVARALDTLG PFDGLLGFSQ 120
  121 GAALAAYVCA LGQAGDPRFP LPRFIILVSG FCPRGLKEPI LQSPMSLPSL HVFGDTDRVI 180
  181 PSQESMQLAS RFLGAVTLTH SGGHFIPAAA SQRQAYLKFL DQFAE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	40.69897
Match:	1fj2A
Description:	Acyl protein thioesterase 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.39629727416851	bayes_pls_golite062009
binding	0.978846093152455	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.603999106175838	bayes_pls_golite062009
structural molecule activity	0.165872846726831	bayes_pls_golite062009
carboxylesterase activity	0.0264147222103929	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: