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View Structure Prediction Details

Protein: PROF4_MOUSE
Organism: Mus musculus
Length: 129 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PROF4_MOUSE.

Description E-value Query
Range		 Subject
Range
PROF1_RICCO - Profilin-1 OS=Ricinus communis GN=PRO1 PE=2 SV=1
 194.0 [0..2] [128..5]
PROF_CHEAL - Profilin OS=Chenopodium album PE=1 SV=1
 193.0 [0..2] [128..5]
PROF_ANACO - Profilin OS=Ananas comosus PE=1 SV=1
 192.0 [0..1] [128..1]
PROF_LITCN - Profilin OS=Litchi chinensis PE=1 SV=1
 191.0 [0..2] [128..5]
gi|125531458 - gi|125531458|gb|EAY78023.1| hypothetical protein OsI_33063 [Oryza sativa Indica Group]
PROFA_ORYSJ - Profilin-A OS=Oryza sativa subsp. japonica GN=Os10g0323600 PE=2 SV=1
PROFA_ORYSA, PRO... - Profilin-A - Oryza sativa (Rice), (Q9FUD1) Profilin A
 189.0 [0..2] [128..5]
gi|77999277 - gi|77999277|gb|ABB16985.1| profilin-like protein [Solanum tuberosum]
 189.0 [0..2] [128..5]
gi|34851176 - gi|34851176|gb|AAP15200.1| profilin-like protein [Humulus scandens]
 189.0 [0..1] [128..1]
gi|60418862, gi|... - gi|60418862|gb|AAX19858.1| profilin 2 [Malus x domestica], gi|60418860|gb|AAX19857.1| profilin 2 [Ma...
 189.0 [0..1] [128..1]
PROF3_HEVBR - Profilin-3 OS=Hevea brasiliensis PE=1 SV=1
 189.0 [0..2] [128..5]

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Predicted Domain #1
Region A:
Residues: [1-129] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHLQNLLLD TLLGTKHVDS AALIKLQEKT LCVTSPGFSV MPSDVRTLLN GFAKNPLLTR  60
   61 REGLYFKEKD YKCVRADDYS LYAKNENTGV VVVKTNMYLV VATYTAGMYP SVCVEATEKL 120
  121 GEYLRKKGN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.0
Match: 1g5uA
Description: Profilin (actin-binding protein)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
actin binding 7.981958446142 bayes_pls_golite062009
cytoskeletal protein binding 6.51470611165788 bayes_pls_golite062009
actin monomer binding 3.80837480536839 bayes_pls_golite062009
phosphatidylinositol-4,5-bisphosphate binding 3.76536709399936 bayes_pls_golite062009
binding 3.26636517628678 bayes_pls_golite062009
protein binding 2.14534188091242 bayes_pls_golite062009
phosphoinositide binding 0.0670083531910797 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle