YRC Public Data Repository - Protein Structure Prediction

Protein:	PSA7L_MOUSE
Organism:	Mus musculus
Length:	250 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PSA7L_MOUSE.

Description	E-value	Query Range	Subject Range
PSA7L_MACFA - Proteasome subunit alpha type-7-like OS=Macaca fascicularis GN=PSMA7L PE=2 SV=1	273.0	[0..1]	[232..1]
gi\|157820507, gi... - gi\|157820507\|ref\|NP_001102354.1\| hypothetical protein LOC364814 [Rattus norvegicus], gi\|149015674\|gb...	273.0	[0..1]	[234..1]
gi\|68303563, gi\|... - gi\|68303563\|ref\|NP_001020267.1\| proteasome alpha 8 subunit isoform 2 [Homo sapiens], gi\|27503801\|gb\|...	270.0	[0..1]	[232..1]
gi\|74145096 - gi\|74145096\|dbj\|BAE27417.1\| unnamed protein product [Mus musculus]	268.0	[0..1]	[231..1]
PSA7_CARAU - Proteasome subunit alpha type-7 OS=Carassius auratus GN=psma7 PE=2 SV=1	268.0	[0..1]	[231..1]
gi\|41351173, gi\|... - gi\|47085943\|ref\|NP_998331.1\| proteasome alpha 8 subunit [Danio rerio], gi\|41351173\|gb\|AAH65608.1\| Zg...	267.0	[0..1]	[231..1]
PSA_PYRAB - Proteasome subunit alpha OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=psmA PE=3 SV=1 PSMA_PYRAB - Proteasome subunit alpha OS=Pyrococcus abyssi GN=psmA PE=3 SV=1	267.0	[0..3]	[231..8]
gi\|114672627 - gi\|114672627\|ref\|XP_523894.2\| PREDICTED: proteasome (prosome, macropain) subunit, alpha type, 8 isof...	267.0	[0..1]	[232..1]

Back

Predicted Domain #1

Region A:
Residues: [1-250]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASRYDRAIT VFSPDGHLFQ VEYAQEAVKK GSTAVGIRGT NIVVLGVEKK SVAKLQDERT  60
   61 VRKICALDDH VCMAFAGLTA DARVVISRAR VECQSHKLTV EDPVTVEYIT RFIATLKQKY 120
  121 TQSNGRRPFG ISALIVGFDD DGIPRLYQTD PSGTYHAWKA NAIGRSAKTV REFLEKNYTE 180
  181 DAISNDKEAI KLAIKALLEV VQSGGKNIEL AIIRRDQPLK MFSAKEIELE VSEIEREKDE 240
  241 AEKTKSKKST

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	70.045757
Match:	1iruD
Description:	Proteasome alpha subunit (non-catalytic)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
endopeptidase activity	6.91642761177919	bayes_pls_golite062009
peptidase activity	6.84511694091156	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	6.5973571808298	bayes_pls_golite062009
hydrolase activity	4.47652590304822	bayes_pls_golite062009
threonine-type endopeptidase activity	2.98214579292788	bayes_pls_golite062009
threonine-type peptidase activity	2.98214579292788	bayes_pls_golite062009
binding	1.75265921676176	bayes_pls_golite062009
nucleic acid binding	1.39216781236247	bayes_pls_golite062009
catalytic activity	1.19663085909195	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: